anti-IKK alpha Antibody
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Catalog number2115
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoIKK alpha Antibody: Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa; and bacteria product LPS. NF-kB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. The long-sought IkB kinase (IKK), which phosphorylates IkB, and mediates IkB degradation and NF-kB activation, was recently identified by several laboratories. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKKa; and IKKβ). IKKa; and IKKβ interact with each other and both are essential for the NF-kB activation. IKKa; specifically phosphorylates IkB-alpha. IKKa; is expressed in a variety of human tissues.
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Gene namesIKK alpha Antibody: IKK1, IKKA, IKBKA, TCF16, NFKBIKA, IKK-alpha, Inhibitor of nuclear factor kappa-B kinase subunit alpha, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase alpha
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Antibodie s labelunlabelled serum
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PurityIKK alpha Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toThis polyclonal antibody has no cross response to IKKb or IKKy.
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AntigenIKK alpha antibody was made against a 17 amino acid peptide near the carboxy terminus of human IKK alpha.
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Immuno applicationELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence
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Antibody adviceIKK alpha antibody can be used for detection of IKK alpha by Western blot 0.5 ug/mL. A 85 kDa band should be detected. Antibody can also be used for immunocytochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideIKK alpha Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atIKK alpha antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman
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Omim nr2327068
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Ncbi nrAF009225
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KDa85 kDa
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Vial with antibodyin solution
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NCBI GENE nr1147
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GENE symbolCHUK
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Antigene nameconserved helix-loop-helix ubiquitous kinase
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SourceHomo sapiens
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Protein nrO15111
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DescriptionThe anti-IKK alpha Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolIKBKE, IKBKB, CHUK, IKBKG
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Short nameanti-IKK alpha Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toIKK a (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameinhibitor of nuclear factor kappa B kinase subunit epsilon
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Synonyms gene name
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-12-02
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Entrez gene record
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Pubmed identfication
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Classification
- I kappa B kinases
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinhibitor of nuclear factor kappa B kinase subunit beta
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Synonyms gene name
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-02-11
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Entrez gene record
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Pubmed identfication
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Classification
- I kappa B kinases
- IKK complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecomponent of inhibitor of nuclear factor kappa B kinase complex
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Synonyms gene
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Synonyms gene name
- conserved helix-loop-helix ubiquitous kinase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-03-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- I kappa B kinases
- IKK complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinhibitor of nuclear factor kappa B kinase regulatory subunit gamma
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Synonyms gene
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Synonyms gene name
- incontinentia pigmenti
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
- inhibitor of nuclear factor kappa B kinase subunit gamma
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2HC-type
- IKK complex
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data