AP-TNAP/ALPL Antibody, Biotin Conjugated

• Catalog number
  bs-1535R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  AP-TNAP/ALPL Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  AP-TNAP/ALPL
• Specificity
  This is a highly specific antibody against AP-TNAP/ALPL.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  50-100/524
• Subcellular location
  Cell membrane
• Source
  KLH conjugated synthetic peptide derived from AP-TNAP/ALPL
• Gene ID number
  11647
• Swiss Prot
  P09242
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Alkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH. Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  Akp2; TNAP; Akp-2; APTNAP; TNSALP; Alkaline phosphatase, tissue-nonspecific isozyme; AP-TNAP; Alkaline phosphatase 2; Alkaline phosphatase liver/bone/kidney isozyme; Alpl
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  AP-TNAP/ALPL   Conjugated  
• Gene symbol
  ALPL, JUND, TFAP2A, TFAP2E, PTPRCAP, AP5B1, TFAP2B, KLF12, TRRAP, PHYHIP
• Short name
  Anti-AP-TNAP/ALPL
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  AP
• Alternative name
  Anti-AP-TNAP/ALPL PAb Biotin
• Alternative technique
  antibodies
• Alternative to gene target
  alkaline phosphatase, liver/bone/kidney, AP-TNAP and APTNAP and HOPS and TNAP and TNSALP, ALPL and IDBG-93194 and ENSG00000162551 and 249, metal ion binding, Extracellular, Alpl and IDBG-199139 and ENSMUSG00000028766 and 11647, ALPL and IDBG-645614 and ENSBTAG00000008951 and 280994

Gene info

• Identity
  HGNC:438
• Gene
  ALPL
• Long gene name
  alkaline phosphatase, biomineralization associated
• Synonyms gene
  • HOPS
• Synonyms gene name
  • alkaline phosphatase, liver/bone/kidney
• Synonyms
  • TNSALP
  • TNALP
  • TNAP
• Synonyms name
  • tissue non-specific alkaline phosphatase
• GenBank acession
  • BC021289
• Locus
  1p36.12
• Discovery year
  1986-01-01
• Entrez gene record
  249
• Pubmed identfication
  • 3532105
  • 3446011
• RefSeq identity
  • NM_000478
• Classification
  • Alkaline phosphatases
• VEGA ID
  OTTHUMG00000002949
• Locus Specific Databases
  • Tissue Nonspecific Alkaline Phosphatase Gene Mutation Database

Gene info

• Identity
  HGNC:6206
• Gene
  JUND
• Long gene name
  JunD proto-oncogene, AP-1 transcription factor subunit
• Synonyms
  • AP-1
• Synonyms name
  • transcription factor jun-D
  • JunD-FL isoform
  • activator protein 1
• Locus
  19p13.11
• Discovery year
  1990-09-10
• Entrez gene record
  3727
• Pubmed identfication
  • 2112242
  • 1903194
• RefSeq identity
  • NM_005354
• Classification
  • Basic leucine zipper proteins
  • Jun transcription factor family
• VEGA ID
  OTTHUMG00000183355

Gene info

• Identity
  HGNC:11742
• Gene
  TFAP2A
• Long gene name
  transcription factor AP-2 alpha
• Synonyms gene
  • TFAP2
  • AP2TF
• Synonyms gene name
  • transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha)
  • transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
• Synonyms
  • AP-2
  • AP-2alpha
• GenBank acession
  • X52611
• Locus
  6p24.3
• Discovery year
  1991-09-12
• Entrez gene record
  7020
• Pubmed identfication
  • 1916817
  • 3063603
• RefSeq identity
  • NM_003220
• Classification
  • Transcription factor AP-2 family
• VEGA ID
  OTTHUMG00000014235

Gene info

• Identity
  HGNC:30774
• Gene
  TFAP2E
• Long gene name
  transcription factor AP-2 epsilon
• Synonyms gene name
  • transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
• Synonyms
  • AP2E
  • AP-2epsilon
• GenBank acession
  • BC041175
• Locus
  1p34.3
• Discovery year
  2004-11-05
• Entrez gene record
  339488
• Pubmed identfication
  • 14636996
• RefSeq identity
  • NM_178548
• Classification
  • Transcription factor AP-2 family
• VEGA ID
  OTTHUMG00000004388

Gene info

• Identity
  HGNC:9667
• Gene
  PTPRCAP
• Long gene name
  protein tyrosine phosphatase receptor type C associated protein
• Synonyms
  • LPAP
  • CD45-AP
• Locus
  11q13.2
• Discovery year
  1996-04-22
• Entrez gene record
  5790
• RefSeq identity
  • NM_005608
• VEGA ID
  OTTHUMG00000150325

Gene info

• Identity
  HGNC:25104
• Gene
  AP5B1
• Long gene name
  adaptor related protein complex 5 subunit beta 1
• Synonyms gene name
  • adaptor-related protein complex 5, beta 1 subunit
  • adaptor related protein complex 5 beta 1 subunit
• Synonyms
  • PP1030
  • AP-5
  • DKFZp761E198
• GenBank acession
  • JQ313135
• Locus
  11q13.1
• Discovery year
  2012-02-27
• Entrez gene record
  91056
• Pubmed identfication
  • 22022230
• RefSeq identity
  • NM_138368
• Classification
  • Adaptor related protein complex 5
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000166593

Gene info

• Identity
  HGNC:11743
• Gene
  TFAP2B
• Long gene name
  transcription factor AP-2 beta
• Synonyms gene name
  • transcription factor AP-2 beta (activating enhancer-binding protein 2 beta)
  • transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
• Synonyms
  • AP2-B
  • AP-2beta
• GenBank acession
  • X95694
• Locus
  6p12.3
• Discovery year
  1995-12-18
• Entrez gene record
  7021
• Pubmed identfication
  • 7555706
  • 8661133
• RefSeq identity
  • NM_003221
• Classification
  • Transcription factor AP-2 family
• VEGA ID
  OTTHUMG00000014836

Gene info

• Identity
  HGNC:6346
• Gene
  KLF12
• Long gene name
  Kruppel like factor 12
• Synonyms
  • AP-2rep
  • HSPC122
  • AP2REP
• Synonyms name
  • KLF12 zinc finger transcriptional repressor
  • AP-2rep transcription factor
  • AP-2 repressor
• GenBank acession
  • AJ243274
• Locus
  13q22.1
• Discovery year
  2000-05-25
• Entrez gene record
  11278
• Pubmed identfication
  • 10704285
• RefSeq identity
  • NM_007249
• Classification
  • Zinc fingers C2H2-type
  • Kruppel like factors
• VEGA ID
  OTTHUMG00000017078

Gene info

• Identity
  HGNC:12347
• Gene
  TRRAP
• Long gene name
  transformation/transcription domain associated protein
• Synonyms gene name
  • transformation/transcription domain-associated protein
• Synonyms
  • TR-AP
  • PAF400
  • Tra1
• GenBank acession
  • AF076974
• Locus
  7q22.1
• Discovery year
  1998-10-06
• Entrez gene record
  8295
• Pubmed identfication
  • 9708738
  • 9885574
• RefSeq identity
  • NM_003496
• Classification
  • MicroRNA protein coding host genes
  • SAGA complex
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000150403

Gene info

• Identity
  HGNC:16865
• Gene
  PHYHIP
• Long gene name
  phytanoyl-CoA 2-hydroxylase interacting protein
• Synonyms gene
  • DYRK1AP3
• Synonyms gene name
  • phytanoyl-CoA hydroxylase interacting protein
  • DYRK1A interacting protein 3
• Synonyms
  • KIAA0273
  • PAHX-AP
• GenBank acession
  • D87463
• Locus
  8p21.3
• Discovery year
  2001-11-16
• Entrez gene record
  9796
• Pubmed identfication
  • 9039502
  • 10686344
• RefSeq identity
  • NM_014759
• VEGA ID
  OTTHUMG00000163776

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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