ATRA; Tretinoin; NSC 122758; Vitamin A Acid; all-trans Retinoic Acid; NSC 122578
Retinoic acid is a metabolite of vitamin A that acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). RAR and RXR heterodimerize and act as ligand-dependent transcriptional regulators, with roles in development, reproduction, immunity, organogenesis, and cancer. Retinoic acid primes embryonic stem cells to become neurons.
Is it cell-permeable?
≥98% by titration
Is this a salt?
Protect from air and light
Maximum time for storage
Yellow solid with an orange tinge
DMSO (20 mg/ml) or Ethanol (0.5 mg/ml)
For cells, cell lines and tissues in culture till half confluency.