CD46/MCP Antibody, ALEXA FLUOR 594

• Catalog number
  bs-1529R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  CD46/MCP Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-CD46/MCP PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CD46/MCP
• Specificity
  This is a highly specific antibody against CD46/MCP.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  250-300/365
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic peptide derived from Mouse CD46
• Gene ID Number
  4179
• Swiss Prot
  P15529
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Mouse
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  MCP; TLX; AHUS2; MIC10; TRA2.10; Membrane cofactor protein; Trophoblast leukocyte common antigen; CD46
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  CD46/MCP  
• Gene symbol
  CD46, CAPG, CCL8, SLC25A33, CCL7, CCL13, CCR2, CCL2
• Short name
  Anti-CD46/MCP
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  CD46/MCP Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies
• Alternative to gene target
  CD46 molecule, complement regulatory protein, AHUS2 and MCP and MIC10 and TLX and TRA2.10, CD46 and IDBG-106372 and ENSG00000117335 and 4179, cadherin binding, Cell surfaces, Cd46 and IDBG-209330 and ENSMUSG00000016493 and 17221, BT.68611 and IDBG-638462 and ENSBTAG00000005397 and 280851

Gene info

• Identity
  HGNC:6953
• Gene
  CD46
• Long gene name
  CD46 molecule
• Synonyms gene
  • MIC10
  • MCP
• Synonyms gene name
  • antigen identified by monoclonal antibody TRA-2-10
  • membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
  • CD46 antigen, complement regulatory protein
  • CD46 molecule, complement regulatory protein
• Synonyms
  • TRA2.10
  • MGC26544
  • TLX
• GenBank acession
  • BC030594
• Locus
  1q32.2
• Discovery year
  1988-08-31
• Entrez gene record
  4179
• Pubmed identfication
  • 7929741
• RefSeq identity
  • NM_172361
• Classification
  • Sushi domain containing
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000036397
• Locus Specific Databases
  • LRG_155

Gene info

• Identity
  HGNC:1474
• Gene
  CAPG
• Long gene name
  capping actin protein, gelsolin like
• Synonyms gene
  • AFCP
• Synonyms gene name
  • capping protein (actin filament), gelsolin-like
• Synonyms
  • MCP
• Synonyms name
  • macrophage capping protein
• GenBank acession
  • M94345
• Locus
  2p11.2
• Discovery year
  1993-12-14
• Entrez gene record
  822
• Pubmed identfication
  • 1322908
  • 12754261
• RefSeq identity
  • NM_001747
• Classification
  • Gelsolin/villins
• VEGA ID
  OTTHUMG00000130183

Gene info

• Identity
  HGNC:10635
• Gene
  CCL8
• Long gene name
  C-C motif chemokine ligand 8
• Synonyms gene
  • SCYA8
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)
  • chemokine (C-C motif) ligand 8
• Synonyms
  • MCP-2
  • HC14
• GenBank acession
  • X99886
• Locus
  17q12
• Discovery year
  1996-11-14
• Entrez gene record
  6355
• Pubmed identfication
  • 9119400
• RefSeq identity
  • NM_005623
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132883

Gene info

• Identity
  HGNC:29681
• Gene
  SLC25A33
• Long gene name
  solute carrier family 25 member 33
• Synonyms gene name
  • solute carrier family 25, member 33
  • solute carrier family 25 (pyrimidine nucleotide carrier), member 33
• Synonyms
  • MGC4399
  • BMSC-MCP
  • PNC1
• GenBank acession
  • AF495714
• Locus
  1p36.22
• Discovery year
  2006-09-21
• Entrez gene record
  84275
• Pubmed identfication
  • 14715278
  • 16949250
• RefSeq identity
  • NM_032315
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000001322

Gene info

• Identity
  HGNC:10634
• Gene
  CCL7
• Long gene name
  C-C motif chemokine ligand 7
• Synonyms gene
  • SCYA6
  • SCYA7
• Synonyms gene name
  • small inducible cytokine A7 (monocyte chemotactic protein 3)
  • chemokine (C-C motif) ligand 7
• Synonyms
  • MCP-3
  • NC28
  • FIC
  • MARC
  • MCP3
• Synonyms name
  • monocyte chemoattractant protein 3
  • monocyte chemotactic protein 3
• GenBank acession
  • AF043338
• Locus
  17q12
• Discovery year
  1993-11-04
• Entrez gene record
  6354
• Pubmed identfication
  • 8461011
• RefSeq identity
  • NM_006273
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132889

Gene info

• Identity
  HGNC:10611
• Gene
  CCL13
• Long gene name
  C-C motif chemokine ligand 13
• Synonyms gene
  • SCYA13
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 13
  • chemokine (C-C motif) ligand 13
• Synonyms
  • MCP-4
  • NCC-1
  • SCYL1
  • CKb10
  • MGC17134
• GenBank acession
  • AJ001634
• Locus
  17q12
• Discovery year
  1997-02-11
• Entrez gene record
  6357
• Pubmed identfication
  • 8661057
• RefSeq identity
  • NM_005408
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132890

Gene info

• Identity
  HGNC:1603
• Gene
  CCR2
• Long gene name
  C-C motif chemokine receptor 2
• Synonyms gene
  • CMKBR2
• Synonyms gene name
  • chemokine (C-C motif) receptor 2
• Synonyms
  • CC-CKR-2
  • CKR2
  • MCP-1-R
  • CD192
  • FLJ78302
• Locus
  3p21.31
• Discovery year
  1995-05-30
• Entrez gene record
  729230
• Pubmed identfication
  • 8146186
• RefSeq identity
  • NM_000647
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000156466

Gene info

• Identity
  HGNC:10618
• Gene
  CCL2
• Long gene name
  C-C motif chemokine ligand 2
• Synonyms gene
  • SCYA2
• Synonyms gene name
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
  • chemokine (C-C motif) ligand 2
• Synonyms
  • MCP1
  • MCP-1
  • MCAF
  • SMC-CF
  • GDCF-2
  • HC11
  • MGC9434
• Synonyms name
  • monocyte chemotactic protein 1, homologous to mouse Sig-je
  • monocyte chemoattractant protein-1
  • monocyte chemotactic and activating factor
  • monocyte secretory protein JE
  • small inducible cytokine subfamily A (Cys-Cys), member 2
• GenBank acession
  • BC009716
• Locus
  17q12
• Discovery year
  1990-07-05
• Entrez gene record
  6347
• Pubmed identfication
  • 2004761
• RefSeq identity
  • NM_002982
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132887

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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