anti-p53AIP1 Antibody

  • Catalog number
    2449
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    p53AIP1 Antibody: The p53 tumor-suppressor protein can induce apoptosis through transcriptional activation of several genes. One such protein p53AIP was initially identified through direct cloning of p53 binding sequences from human genomic DNA. Its expression is inducible by p53 following p53 phosphorylation on Ser-46, and ectopic expression of p53AIP leads to apoptotic cell death. Both the phosphorylation of p53 and the induction of p53AIP were blocked by inhibiting the expression of p53DINP1 by the introduction of antisense oligonucleotides to p53DINP1, suggesting that the apoptosis associated with p53AIP expression is regulated by p53DINP1. Finally, as adenovirus-mediated introduction of p53AIP has been shown to suppress tumor growth in vivo, it has been suggested that p53AIP gene transfer may become a useful strategy for the treatment of p53-resistant cancers. Three isoforms of p53AIP are known to exist; this antibody will detect all three.
  • Gene names
    p53AIP1 Antibody: P53AIP1, p53-regulated apoptosis-inducing protein 1, p53AIP1
  • Antibodie s label
    unlabelled serum
  • Purity
    p53AIP1 Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Antigen
    p53AIP1 antibody was made against a 15 amino acid synthetic peptide from near the amino terminus of human p53AIP1.
  • Immuno application
    ELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence
  • Antibody advice
    p53AIP1 antibody can be used for detection of p53AIP1 by Western blot at 4 - 8 ug/mL. Antibody can also be used for immunocytochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.
  • Suspention pH azide
    p53AIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    p53AIP1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human
  • Omim nr
    10798768
  • Ncbi nr
    BAB16421
  • Vial with antibody
    in solution
  • NCBI GENE nr
    63970
  • GENE symbol
    TP53AIP1
  • Antigene name
    tumor protein p53 regulated apoptosis inducing protein 1
  • Source
    Homo sapiens
  • Protein nr
    Q9HCN2
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    p53AIP1  
  • Gene symbol
    TP53AIP1
  • Short name
    anti-p53AIP1 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody top53AIP1 (antibody to-)
  • Alternative technique
    antibodies
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products
Filters
Contact
Chat with gentaur.com employee