Ki-67 (Proliferation Marker) Antibody
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Catalog number
bs-2130R
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Price
Please ask
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Size
0.1ml
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Long name
Ki-67 (Proliferation Marker) Antibody
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Also known as
Ki-67 (Proliferation Marker) Antibody
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
Ki-67 proliferation Marker
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Specificity
This is a highly specific antibody against Ki-67 proliferation Marker.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen range
1250-1300/3256
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Subcellular location
Nucleus
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ki67
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Gene ID number
4288
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Swiss Prot
P46013
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Tested Applications
IHC-P, IF(IHC-P), IF(ICC)
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Recommended dilutions
IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
KIA; MIB-; MIB-1; PPP1R15; Antigen KI-67; MKI67
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
MKI67P1, MKI67
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Short name
Anti-Ki-67 proliferation Marker
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Technique
Antibody, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA.
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
Ki-67 (Proliferation Marker) Antibody
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Alternative technique
antibodies
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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