NFkB, p65, phosphorylated (Ser276), Control Peptide (NF-kB, Nuclear Factor kappa B, RelA)

• Catalog number
  MBS658410
• Price
  Please ask
• Size
  1 mg

• Products_type
  Peptide
• Products_short_name
  [NFkB, p65]
• Other_names
  [NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform c; NF-kappa-B inhibitor-interacting Ras-like protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; kappa B-Ras protein 2; I-kappa-B-interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like 2; I-kappa-B-interacting Ras-like protein 2]
• Other_gene_names
  [NKIRAS2; NKIRAS2; KBRAS2; kappaB-Ras2; KBRAS2; Kappa B-Ras protein 2; KappaB-Ras2]
• Reactivity
  Human
• Specificity
  Block specific interaction of anti-pS276 with pS276 phosphorylated p65.
• Purity
  Highly Purified95% specific peptide
• Form
  Supplied as a liquid in PBS, 0.1% sodiom azide. No stabilizing proteins added.
• Storage_stability
  Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer._x000B_
• Tested_application
  ELISA (EL/EIA)
• Description
  Isotype or positive controls by peptides, antibodies and deactivated samples. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
• Gene
  NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory

• Gene target
  NFkB   p65   phosphorylated   Ser276   Peptide   NF-kB   Factor   kappa   RelA  
• Gene symbol
  NFE4, NFE2, NEFH, NFKB1, INA, NFASC, NFATC1, NFYC, NFATC2, NFIL3
• Short name
  NFkB, p65, phosphorylated (Ser276), Control Peptide (NF-kB, Factor kappa B, RelA)
• Technique
  Control, peptide, controls, peptides
• Alternative name
  NFkB, p65, phosphorylated (Ser276), reference short protein sequence (NF-kB, Nuclear Factor kappa B, v-v-rel reticuloendotheliosis viral oncogene homolog (avian) reticuloendotheliosis viral oncogene homolog A (avian))
• Alternative technique
  peptides, controls
• Alternative to gene target
  v-rel reticuloendotheliosis viral oncogene homolog A (avian), NFKB3 and p65, RELA and IDBG-57543 and ENSG00000173039 and 5970, ankyrin repeat binding, nuclei, Rela and IDBG-132298 and ENSMUSG00000024927 and 19697, BT.26220 and IDBG-644222 and ENSBTAG00000013895 and 508233
• Tissue
  control

Gene info

• Identity
  HGNC:29902
• Gene
  NFE4
• Long gene name
  nuclear factor, erythroid 4
• Synonyms
  • NF-E4
• Locus
  7q22.1
• Discovery year
  2013-08-23
• Entrez gene record
  58160
• Pubmed identfication
  • 11003662
• RefSeq identity
  • NR_166510
• VEGA ID
  OTTHUMG00000157208

Gene info

• Identity
  HGNC:7780
• Gene
  NFE2
• Long gene name
  nuclear factor, erythroid 2
• Synonyms gene name
  • nuclear factor (erythroid-derived 2), 45kD
  • nuclear factor (erythroid-derived 2), 45kDa
• Synonyms
  • NF-E2
• GenBank acession
  • BC005044
• Locus
  12q13.13
• Discovery year
  1993-11-03
• Entrez gene record
  4778
• Pubmed identfication
  • 8355703
• RefSeq identity
  • NM_006163
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000169761

Gene info

• Identity
  HGNC:7737
• Gene
  NEFH
• Long gene name
  neurofilament heavy chain
• Synonyms gene name
  • neurofilament, heavy polypeptide 200kDa
  • neurofilament heavy polypeptide
  • neurofilament heavy
• Synonyms
  • NF-H
  • NFH
• Locus
  22q12.2
• Discovery year
  1988-08-31
• Entrez gene record
  4744
• RefSeq identity
  • NM_021076
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000151155
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

Gene info

• Identity
  HGNC:6057
• Gene
  INA
• Long gene name
  internexin neuronal intermediate filament protein alpha
• Synonyms gene
  • NEF5
• Synonyms gene name
  • internexin neuronal intermediate filament protein, alpha
• Synonyms
  • NF-66
• GenBank acession
  • S78296
• Locus
  10q24.33
• Discovery year
  1999-03-24
• Entrez gene record
  9118
• Pubmed identfication
  • 7769995
• RefSeq identity
  • NM_032727
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000018986

Gene info

• Identity
  HGNC:29866
• Gene
  NFASC
• Long gene name
  neurofascin
• Synonyms gene name
  • neurofascin homolog (chicken)
• Synonyms
  • NRCAML
  • KIAA0756
  • FLJ46866
  • NF
• GenBank acession
  • AK027553
• Locus
  1q32.1
• Discovery year
  2005-11-22
• Entrez gene record
  23114
• Pubmed identfication
  • 1377696
  • 8672144
• RefSeq identity
  • NM_001005388
• Classification
  • Ig-like cell adhesion molecule family
  • I-set domain containing
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000151697

Gene info

• Identity
  HGNC:7775
• Gene
  NFATC1
• Long gene name
  nuclear factor of activated T cells 1
• Synonyms gene name
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • nuclear factor of activated T-cells 1
• Synonyms
  • NF-ATC
  • NFATc
  • NFAT2
• GenBank acession
  • U08015
• Locus
  18q23
• Discovery year
  1994-11-16
• Entrez gene record
  4772
• Pubmed identfication
  • 8202141
• RefSeq identity
  • NM_172390
• Classification
  • Nuclear factors of activated T-cells
  • IPT domain containing
• VEGA ID
  OTTHUMG00000132897

Gene info

• Identity
  HGNC:7806
• Gene
  NFYC
• Long gene name
  nuclear transcription factor Y subunit gamma
• Synonyms gene name
  • nuclear transcription factor Y, gamma
• Synonyms
  • CBF-C
  • NF-YC
• GenBank acession
  • U78774
• Locus
  1p34.2
• Discovery year
  1996-10-26
• Entrez gene record
  4802
• Pubmed identfication
  • 8921405
  • 9249075
• RefSeq identity
  • NM_014223
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000007729

Gene info

• Identity
  HGNC:7776
• Gene
  NFATC2
• Long gene name
  nuclear factor of activated T cells 2
• Synonyms gene name
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • nuclear factor of activated T-cells 2
• Synonyms
  • NF-ATP
  • NFATp
  • NFAT1
• GenBank acession
  • U43342
  • U43341
• Locus
  20q13.2
• Discovery year
  1994-11-16
• Entrez gene record
  4773
• Pubmed identfication
  • 8202141
• RefSeq identity
  • NM_012340
• Classification
  • IPT domain containing
  • Nuclear factors of activated T-cells
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000032747

Gene info

• Identity
  HGNC:7787
• Gene
  NFIL3
• Long gene name
  nuclear factor, interleukin 3 regulated
• Synonyms gene
  • IL3BP1
• Synonyms gene name
  • interleukin-3 binding protein 1
• Synonyms
  • E4BP4
  • NFIL3A
  • NF-IL3A
• Synonyms name
  • E4 promoter-binding protein
  • adenovirus E4 promoter region binding protein
• GenBank acession
  • X64318
• Locus
  9q22.31
• Discovery year
  1995-02-13
• Entrez gene record
  4783
• Pubmed identfication
  • 7565758
  • 1620116
• RefSeq identity
  • NM_005384
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000020209

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