SOCS 1(Suppressor of Cytokine Signalling 1, Janus kinase (JAK) binding protein, STAT-induced STAT inhibitor, SSI-1)[SOCS 1(Suppressor of Cytokine Signalling 1, Janus kinase]

  • Catalog number
    MBS626954
  • Price
    Please ask
  • Size
    NA
  • Products_type
    Antibody
  • Reactivity
    Human, Mouse
  • Description
    Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
  • Gene target
    SOCS   Suppressor   Cytokine   Signalling   Janus   kinase   JAK   binding   protein   STAT   STAT   inhibitor   SSI-1   [SOCS   Suppressor   Cytokine   Signalling   Janus   kinase]  
  • Gene symbol
    SOCS1, SOCS3, SOCS2, CISH, STAT6, SOAT1, SOCS5, JAK3, IGHVII-1-1, MIR1-1
  • Short name
    SOCS 1(Suppressor of Cytokine Signalling 1, Janus kinase (JAK) binding protein, STAT- STAT inhibitor, SSI-1)[SOCS 1(Suppressor of Cytokine Signalling 1, Janus kinase]
  • Host
    Rabbit
  • Alternative name
    SOCS 1(Suppressor on Cytokine Signalling 1, Janus phosphorylation catalyst (JAK) binding protein, Signal transducer and activation on transcription-induced Signal transducer and activation on transcription suppressor, SSI-1)[SOCS 1(Suppressor on Cytokine Signalling 1, Janus phosphorylation catalyst]
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
    HGNC:5670
  • Gene
    IGHVII-1-1
  • Long gene name
    immunoglobulin heavy variable (II)-1-1 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable (II)-1-1
    • immunoglobulin heavy variable (II)-1-1 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
    14q32.33
  • Discovery year
    2000-04-17
  • Entrez gene record
    28377
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
    OTTHUMG00000152325
Gene info
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SOCS 1 Suppressor of Cytokine Signalling 1 Janus kinase JAK
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