FLIP-L (FLICE-like Inhibitory Protein Long Form, CFLAR, CASH, CASP8AP1, CLARP, MRIT, CASP8 and FADD-like Apoptosis Regulator, Caspase Homolog, CASH, Caspase-eight-related Protein, Casper, Caspase-like Apoptosis Regulatory Protein, CLARP, Cellular FLICE-li

• Catalog number
  MBS623794
• Price
  Please ask
• Size
  0,1 mg

• Other size
  please contact us to order other different size
• Description
  This 1 is suited for programmed cell-death studies. Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

• Gene target
  FLIP-L   FLICE-like   Inhibitory   Protein   Long   Form   CFLAR   CASH   CASP8AP1   CLARP   MRIT   CASP8   FADD-like   Regulator   Caspase   Homolog   CASH   Caspase-eight-related   Protein   Casper   Caspase-like   Regulatory   Protein   CLARP   Cellular   FLICE-li  
• Gene symbol
  CFLAR, CASP8, CASP10, FADD, CFLAR-AS1, CPT1A, POM121L2, L3MBTL2, CLDN10, RPL32P1
• Short name
  FLIP-L (FLICE-like Inhibitory Protein Long Form, CFLAR, CASH, CASP8AP1, CLARP, MRIT, CASP8 FADD-like Apoptosis Regulator, Caspase Homolog, CASH, Caspase-eight- Protein, Casper, Caspase-like Apoptosis Regulatory Protein, CLARP, Cellular FLICE-li
• Technique
  apoptosis, cellular, apoptosis pathway
• Alternative name
  FLIP-L (FLICE-like Inhibitory Protein large Form, CASP8 and Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain-like apoptosis regulator, CASH, CASP8AP1, CLARP, MRIT, caspase 8, apoptosis-related cysteine peptidase and Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain-like programmed cellular destruction Regulator, caspase Homolog, CASH, caspase-eight-related Protein, Casper, caspase-like programmed cellular destruction Regulatory Protein, CLARP, Cellular FLICE-li
• Alternative technique
  celldeath
• Alternative to gene target
  Fas (TNFRSF6)-associated via death domain, MORT1, FADD and IDBG-62144 and ENSG00000168040 and 8772, identical protein binding, Plasma membranes, Fadd and IDBG-212910 and ENSMUSG00000031077 and 14082, FADD and IDBG-645056 and ENSBTAG00000018274 and 493720
• Tissue
  cellular

Gene info

• Identity
  HGNC:1876
• Gene
  CFLAR
• Long gene name
  CASP8 and FADD like apoptosis regulator
• Synonyms gene
  • CASP8AP1
• Synonyms gene name
  • CASP8 and FADD-like apoptosis regulator
• Synonyms
  • CASH
  • Casper
  • CLARP
  • FLAME
  • FLIP
  • I-FLICE
  • MRIT
  • c-FLIP
  • cFLIP
• GenBank acession
  • AF005774
• Locus
  2q33.1
• Discovery year
  1999-05-07
• Entrez gene record
  8837
• Pubmed identfication
  • 9208847
  • 9217161
• RefSeq identity
  • NM_003879
• Classification
  • Receptor ligands
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132819

Gene info

• Identity
  HGNC:1509
• Gene
  CASP8
• Long gene name
  caspase 8
• Synonyms gene name
  • caspase 8, apoptosis-related cysteine protease
  • caspase 8, apoptosis-related cysteine peptidase
• Synonyms
  • MCH5
  • MACH
  • FLICE
  • Casp-8
• GenBank acession
  • U60520
• Locus
  2q33.1
• Discovery year
  1996-11-11
• Entrez gene record
  841
• Pubmed identfication
  • 8681376
  • 8681377
• RefSeq identity
  • NM_001228
• Classification
  • Caspases
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132821
• Locus Specific Databases
  • CASP8base: Mutation registry for Caspase 8 deficiency
  • LRG_34

Gene info

• Identity
  HGNC:1500
• Gene
  CASP10
• Long gene name
  caspase 10
• Synonyms gene name
  • caspase 10, apoptosis-related cysteine protease
  • caspase 10, apoptosis-related cysteine peptidase
• Synonyms
  • MCH4
  • FLICE-2
• Synonyms name
  • FAS-associated death domain protein interleukin-1B-converting enzyme 2
• GenBank acession
  • U60519
• Locus
  2q33.1
• Discovery year
  1997-04-21
• Entrez gene record
  843
• Pubmed identfication
  • 8755496
• RefSeq identity
  • NM_032977
• Classification
  • Caspases
  • Death effector domain containing
  • Death inducing signaling complex
• VEGA ID
  OTTHUMG00000132818
• Locus Specific Databases
  • CASP10base: Mutation registry for Autoimmune lymphoproliferative syndrome, type II (ALPS2)
  • LRG_33

Gene info

• Identity
  HGNC:3573
• Gene
  FADD
• Long gene name
  Fas associated via death domain
• Synonyms gene name
  • Fas (TNFRSF6)-associated via death domain
• Synonyms
  • MORT1
  • GIG3
• Synonyms name
  • Fas-associating protein with death domain
  • Fas-associating death domain-containing protein
  • mediator of receptor-induced toxicity
  • growth-inhibiting gene 3 protein
• GenBank acession
  • U24231
• Locus
  11q13.3
• Discovery year
  1999-05-07
• Entrez gene record
  8772
• Pubmed identfication
  • 7536190
  • 7538907
• RefSeq identity
  • NM_003824
• Classification
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000167264
• Locus Specific Databases
  • LRG_228

Gene info

• Identity
  HGNC:14437
• Gene
  CFLAR-AS1
• Long gene name
  CFLAR antisense RNA 1
• Synonyms gene
  • ALS2CR10
• Synonyms gene name
  • amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 10
  • CFLAR antisense RNA 1 (non-protein coding)
• GenBank acession
  • AB053312
• Locus
  2q33.1
• Discovery year
  2001-01-26
• Entrez gene record
  65072
• Pubmed identfication
  • 27855375
• RefSeq identity
  • NR_040030
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000154713

Gene info

• Identity
  HGNC:2328
• Gene
  CPT1A
• Long gene name
  carnitine palmitoyltransferase 1A
• Synonyms gene
  • CPT1
• Synonyms gene name
  • carnitine palmitoyltransferase 1A (liver)
• Synonyms
  • CPT1-L
  • L-CPT1
• GenBank acession
  • L39211
• Locus
  11q13.3
• Discovery year
  1995-05-30
• Entrez gene record
  1374
• Pubmed identfication
  • 7892212
  • 9070950
• RefSeq identity
  • NM_001876
• VEGA ID
  OTTHUMG00000167892

Gene info

• Identity
  HGNC:13973
• Gene
  POM121L2
• Long gene name
  POM121 transmembrane nucleoporin like 2
• Synonyms gene name
  • POM121 membrane glycoprotein-like 2 (rat)
  • POM121 membrane glycoprotein-like 2
  • POM121 transmembrane nucleoporin-like 2
• Synonyms
  • POM121-L
• GenBank acession
  • AL021808
• Locus
  6p22.1
• Discovery year
  2001-07-20
• Entrez gene record
  94026
• RefSeq identity
  • NM_033482
• VEGA ID
  OTTHUMG00000014475

Gene info

• Identity
  HGNC:18594
• Gene
  L3MBTL2
• Long gene name
  L3MBTL histone methyl-lysine binding protein 2
• Synonyms gene name
  • l(3)mbt-like 2 (Drosophila)
  • L3MBTL2, polycomb repressive complex 1 subunit
• Synonyms
  • H-l(3)mbt-l
  • DKFZP761I141
  • dJ756G23.3
• GenBank acession
  • AJ305226
• Locus
  22q13.2
• Discovery year
  2002-04-29
• Entrez gene record
  83746
• Pubmed identfication
  • 11682070
  • 21596310
• RefSeq identity
  • NM_031488
• Classification
  • MBT domain containing
• VEGA ID
  OTTHUMG00000150942

Gene info

• Identity
  HGNC:2033
• Gene
  CLDN10
• Long gene name
  claudin 10
• Synonyms
  • OSP-L
  • CPETRL3
• GenBank acession
  • U89916
• Locus
  13q32.1
• Discovery year
  1999-01-22
• Entrez gene record
  9071
• Pubmed identfication
  • 18025272
• RefSeq identity
  • NM_006984
• Classification
  • Claudins
• VEGA ID
  OTTHUMG00000017217

Gene info

• Identity
  HGNC:10339
• Gene
  RPL32P1
• Long gene name
  ribosomal protein L32 pseudogene 1
• Synonyms gene
  • RPL32P
• Synonyms gene name
  • ribosomal protein L32 pseudogene
• Synonyms
  • RPL32-L
• GenBank acession
  • X02228
• Locus
  6p21.32
• Discovery year
  2009-03-01
• Entrez gene record
  6163
• Pubmed identfication
  • 3866218
  • 19123937
• RefSeq identity
  • NG_000869
• VEGA ID
  OTTHUMG00000031191

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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