Recombinant Human NAD-dependent protein deacetylase sirtuin-1 (SIRT1)

Products_type

Recombinant Protein
Products_short_name

[NAD-dependent protein deacetylase sirtuin-1 (SIRT1)]
Products_name_syn

[Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2; Cleaved into the following chain: SirtT1 75 kDa fragment; 75SirT1]
Other_names

[NAD-dependent protein deacetylase sirtuin-1 isoform b; NAD-dependent protein deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; sirtuin 1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2]
Products_gene_name

[SIRT1]
Other_gene_names

[SIRT1; SIRT1; SIR2; SIR2L1; SIR2alpha; SIR2L1; hSIRT1; hSIR2; 75SirT1]
Purity

Greater than 90% as determined by SDS-PAGE.
Form

Lyophilized or liquid (Format to be determined during the manufacturing process)
Storage_stability

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

NAD-dependent protein deacetylase sirtuin-1 SIRT1
Gene symbol

SIRT1, SIRT1-AS
Short name

Recombinant NAD-dependent protein deacetylase sirtuin-1 (SIRT1)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E Coli or Yeast or Baculovirus or Mammalian Cell
Species

Human, Humans
Alternative name

Rec. H. sapiens Nicotinamide adenine dinucleotide-dependent protein deacetylase sirtuin-1 (sirtuin 1)
Alternative technique

rec
Alternative to gene target

sirtuin 1, SIR2L1, SIRT1 and IDBG-75847 and ENSG00000096717 and 23411, keratin filament binding, nuclei, Sirt1 and IDBG-159441 and ENSMUSG00000020063 and 93759, SIRT1 and IDBG-629119 and ENSBTAG00000014023 and 613629

Identity

HGNC:14929
Gene

SIRT1
Long gene name

sirtuin 1
Synonyms gene name
- sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1
- sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
Synonyms
- SIR2L1
GenBank acession
- AF083106
Locus

10q21.3
Discovery year

2001-03-20
Entrez gene record

23411
Pubmed identfication
- 10381378
RefSeq identity
- NM_012238
Classification
- eNoSC complex
- Sirtuins
VEGA ID

OTTHUMG00000018340

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data