MEF2C Antibody

• Catalog number
  A1006-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  MEF2C
• Target Alternative Name
  Myocyte-specific enhancer factor 2C, MEF2C
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  synthetic human MEF2C peptide (Gln 365 – Asp 400)
• Accession
  Q06413
• Gene Id
  4208
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  100 µl antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Purification
  Affinity purified rabbit IgG
• Application
  Western Blot, Immunofluorescent staining, Immunohistochemistry
• Positive Control
  Western blot
• Application And Usages
  Western Blot 1:1000; Immunofluorescent staining 1:10~50; Immunohistochemistry 1:10~50
• Description
  Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MEF2C  
• Gene symbol
  MEF2C, MEF2C-AS1, MEF2C-AS2
• Short name
  MEF2C Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  myocyte enhancer factor 2C (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  myocyte enhancer factor 2C, C5DELq14.3 and DEL5q14.3, MEF2C and IDBG-33077 and ENSG00000081189 and 4208, HMG box domain binding, nuclei, Mef2c and IDBG-170220 and ENSMUSG00000005583 and 17260, MEF2C and IDBG-646539 and ENSBTAG00000020701 and 512254

Gene info

• Identity
  HGNC:6996
• Gene
  MEF2C
• Long gene name
  myocyte enhancer factor 2C
• GenBank acession
  • AL833268
• Locus
  5q14.3
• Discovery year
  1995-02-08
• Entrez gene record
  4208
• Pubmed identfication
  • 8455629
• RefSeq identity
  • NM_002397
• Classification
  • Myocyte enhancer factor 2 proteins
  • MADS box family
• VEGA ID
  OTTHUMG00000162634

Gene info

• Identity
  HGNC:48908
• Gene
  MEF2C-AS1
• Long gene name
  MEF2C antisense RNA 1
• GenBank acession
  • CD702404
• Locus
  5q14.3
• Discovery year
  2013-07-01
• Entrez gene record
  101929423
• Pubmed identfication
  • 23801869
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000162630

Gene info

• Identity
  HGNC:53115
• Gene
  MEF2C-AS2
• Long gene name
  MEF2C antisense RNA 2
• Synonyms
  • CTC-467M3.1
• Locus
  5q14.3
• Discovery year
  2017-02-10
• Pubmed identfication
  • 28103885
• Classification
  • Antisense RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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