Dorzolamide hydrochloride

Alternative_name

(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b] thiopyran-2-sulfonamide;hydrochloride; Trusopt; MK-507; L-671, 152
Description

Dorzolamide Hydrochloride is an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate ions. Distributed throughout many cells and tissues, various carbonic anhydrases play important roles in mineral and metabolic homeostasis. An antiglaucoma agent.
CAS Number

130693-82-2
Structure Available

Yes
Salt Form

No
Molecular Formula

C₁₀H₁₇ClN₂O₄S₃
Molecular Weight

360.89
Cell Permeable

Yes
Purity

≥98% by HPLC
Solubilities

DMSO
Handling

Protect from air and light
Tag Line

A carbonic anhydrase inhibitor
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

36 months
MDL Number

MFCD00884659
PubChem CID

6918132
PubChem CID Link
SMILES

CCNC1CC(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C.Cl
InChi

InChI=1S/C10H16N2O4S3.ClH/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16;/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16);1H/t6-,8-;/m0./s1
InChi Key

OSRUSFPMRGDLAG-QMGYSKNISA-N
Data Sheet Link
MSDS Available

Yes