anti-p53R2 Antibody

• Catalog number
  2383
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  p53R2 Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and gamma-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumor suppression.
• Gene names
  p53R2 Antibody: P53R2, MTDPS8A, MTDPS8B, P53R2, Ribonucleoside-diphosphate reductase subunit M2 B, TP53-inducible ribonucleotide reductase M2 B, p53R2
• Antibodie s label
  unlabelled serum
• Purity
  p53R2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  p53R2 antibody was made against a 16 amino acid peptide near the amino terminus of human p53R2.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  p53R2 antibody can be used for detection of p53R2 by Western blot at 0.5 to 1 ug/mL. A 39 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 1 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  p53R2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  p53R2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  7229086
• Ncbi nr
  BAA92434
• KDa
  39 kDa
• Vial with antibody
  in solution
• NCBI GENE nr
  50484
• GENE symbol
  RRM2B
• Antigene name
  ribonucleotide reductase M2 B (TP53 inducible)
• Source
  Homo sapiens
• Protein nr
  Q7LG56
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  p53R2  
• Gene symbol
  RRM2B
• Short name
  anti-p53R2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody top53R2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17296
• Gene
  RRM2B
• Long gene name
  ribonucleotide reductase regulatory TP53 inducible subunit M2B
• Synonyms gene name
  • ribonucleotide reductase M2 B (TP53 inducible)
• Synonyms
  • p53R2
• GenBank acession
  • AB036532
• Locus
  8q22.3
• Discovery year
  2002-01-14
• Entrez gene record
  50484
• Pubmed identfication
  • 10716435
  • 10980602
  • 17486094
• VEGA ID
  OTTHUMG00000164776
• Locus Specific Databases
  • LRG_788

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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