TIP60 Antibody
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Catalog number6126-50
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PricePlease ask
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Size50 μg
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Antibody TargetTIP60
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Target Alternative NameLysine Acetyltransferase 5; KAT5
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Antibody TypePolyclonal
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Species ReactivitiesHuman, chimpanzee, orangutan, equine, canine, mouse, bovine, rat, opossum, zebrafish, xenopus
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Immunogen SequenceSynthetic peptide within the region of human TIP60 amino acids 480-530.
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AccessionQ92993
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Gene Id10524
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AppearanceColorless liquid
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FormLiquid
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Formulation50 µg of antibody in 100 µl PBS containing 0.05% BSA and 0.05% sodium azide.
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PurificationProtein A purified
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ApplicationWestern blot, Immunohistochemistry
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Positive ControlWestern blot: Human brain lysate, mouse brain lysate, rat brain lysate
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Application And UsagesWestern blot: 0.25-1.0 µg/ml, IHC (paraffin embedded sections): 5 µg/ml. However, the optimal conditions should be determined individually.
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DescriptionTIP60, originally isolated as an HIV-1 TAT-interactive protein, is known to interact with the viral TAT protein that leads to HTATIP polyubiquitination and targets it for degradation. It belongs to the MYST family of histone acetyltransferases (HATs). TIP60 is a catalytic subunit of the NuA4 HAT complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. A co-regulator of transcription factors, TIP60 either promotes or suppresses tumorigenesis. TIP60 is an enzyme that has a role in DNA repair and apoptosis and is thoμght to play an important role in signal transduction.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedVerified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolKAT5
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Short nameTIP60 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameTIP60 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namelysine acetyltransferase 5
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Synonyms gene
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Synonyms gene name
- HIV-1 Tat interactive protein, 60kDa
- K(lysine) acetyltransferase 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-04-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2HC-type
- MYST type domain containing lysine acetyltransferases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data