DR3-mIgG2a, Fc Fusion Protein, Recombinant (TNF receptor superfamily member 25, TNFRSF25, LAMP. LARD, APO3, Apo-3, APO-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, DDR3, Death receptor 3, DR3, L[DR3-mIgG2a, Fc Fusion Protein]

  • Catalog number
    MBS635714
  • Price
    Please ask
  • Size
    NA
  • Products_type
    Recombinant Protein
  • Description
    This 1 is suited for programmed cell-death studies. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene
    Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
  • Gene target
  • Gene symbol
    TNFRSF25, TNF, LAMP3, TNFRSF1A, LSAMP, TRAM1, TNFRSF1B, AIRN, TNFSF10, FAS
  • Short name
    DR3-mIgG2a, Fc Protein, Recombinant (TNF receptor superfamily member 25, TNFRSF25, LAMP. LARD, APO3, Apo-3, APO-3, Apoptosis- receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, DDR3, Death receptor 3, DR3, L[DR3-mIgG2a, Fc Protein]
  • Technique
    Recombinant, apoptosis, FC, apoptosis pathway, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Host
    CHO cells
  • Alternative name
    DR3-mIgG2a, fragment c Fusion Protein, Rec. (tumor necrosis factor receptor supergroup member 25, tumor necrosis factor receptor superfamily, member 25, LAMP. LARD, APO3, Apo-3, APO-3, programmed cellular destruction-inducing receptor AIR, programmed cellular destruction-mediating receptor DR3, programmed cellular destruction-mediating receptor TRAMP, DDR3, Death receptor 3, DR3, L[DR3-mIgG2a, fragment c Fusion Protein]
  • Alternative technique
    rec, celldeath
  • Alternative to gene target
    tumor necrosis factor receptor superfamily, member 25, APO-3 and DDR3 and DR3 and LARD and TNFRSF12 and TR3 and TRAMP and WSL-1 and WSL-LR, TNFRSF25 and IDBG-227097 and ENSG00000215788 and 8718, protein binding, Extracellular, Tnfrsf25 and IDBG-206339 and ENSMUSG00000024793 and 85030, BT.30010 and IDBG-633838 and ENSBTAG00000006519 and 783432
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
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Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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