DR3-mIgG2a, Fc Fusion Protein, Recombinant (TNF receptor superfamily member 25, TNFRSF25, LAMP. LARD, APO3, Apo-3, APO-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, DDR3, Death receptor 3, DR3, L[DR3-mIgG2a, Fc Fusion Protein]
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Catalog numberMBS635714
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PricePlease ask
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SizeNA
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Products_typeRecombinant Protein
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DescriptionThis 1 is suited for programmed cell-death studies. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbolTNFRSF25, TNF, LAMP3, TNFRSF1A, LSAMP, TRAM1, TNFRSF1B, AIRN, TNFSF10, FAS
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Short nameDR3-mIgG2a, Fc Protein, Recombinant (TNF receptor superfamily member 25, TNFRSF25, LAMP. LARD, APO3, Apo-3, APO-3, Apoptosis- receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, DDR3, Death receptor 3, DR3, L[DR3-mIgG2a, Fc Protein]
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TechniqueRecombinant, apoptosis, FC, apoptosis pathway, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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HostCHO cells
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Alternative nameDR3-mIgG2a, fragment c Fusion Protein, Rec. (tumor necrosis factor receptor supergroup member 25, tumor necrosis factor receptor superfamily, member 25, LAMP. LARD, APO3, Apo-3, APO-3, programmed cellular destruction-inducing receptor AIR, programmed cellular destruction-mediating receptor DR3, programmed cellular destruction-mediating receptor TRAMP, DDR3, Death receptor 3, DR3, L[DR3-mIgG2a, fragment c Fusion Protein]
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Alternative techniquerec, celldeath
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Alternative to gene targettumor necrosis factor receptor superfamily, member 25, APO-3 and DDR3 and DR3 and LARD and TNFRSF12 and TR3 and TRAMP and WSL-1 and WSL-LR, TNFRSF25 and IDBG-227097 and ENSG00000215788 and 8718, protein binding, Extracellular, Tnfrsf25 and IDBG-206339 and ENSMUSG00000024793 and 85030, BT.30010 and IDBG-633838 and ENSBTAG00000006519 and 783432
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 25
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
- tumor necrosis factor receptor superfamily, member 25
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelysosomal associated membrane protein 3
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Synonyms gene name
- lysosomal-associated membrane protein 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-29
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Entrez gene record
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Pubmed identfication
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Classification
- Lysosome associated membrane proteins
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namelimbic system associated membrane protein
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Synonyms gene name
- limbic system-associated membrane protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-06-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- I-set domain containing
- IgLON cell adhesion molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametranslocation associated membrane protein 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-04-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- TLC domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameantisense of IGF2R non-protein coding RNA
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Synonyms gene name
- antisense of IGF2R RNA (non-protein coding)
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Synonyms
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Synonyms name
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Locus
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Discovery year2008-11-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Long non-coding RNAs with non-systematic symbols
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF superfamily member 10
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 10
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Pubmed identfication
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Classification
- CD molecules
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameFas cell surface death receptor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 6
- Fas (TNF receptor superfamily, member 6)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-06-25
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
- Death inducing signaling complex
- CD molecules
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data