Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Polyclonal Antibody (Rat, Pig), HRP

• Catalog number
  PAB367Po01-1ml-HRP
• Price
  Please ask
• Size
  1ml

• Description
  A Rabbit polyclonal antibody against Rat, Pig Vascular Endothelial Growth Factor Receptor 2 (VEGFR2). This antibody is labeled with HRP.
• Specifications
  Host: Rabbit; Species Reactivity: Rat, Pig; Clonality: polyclonal; Tested applications: WB; Concentration: 500ug/ml; Isotype: IgG; Conjugation: HRP
• Additional_information
  Sequence of the immunogen: VEGFR2 (Phe8~Val290); Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Storage_and_shipping
  Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
• Notes
  Research Use Only.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Conjugation
  HRP Conjugated
• About
  Pigs and the smaller guinea pigs are frequent used as models for humans. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Group
  Polyclonals and antibodies
• Latin name
  Rattus norvegicus
• French translation
  anticorps

• Gene target
  Vascular   Endothelial   Growth   Factor   Receptor   VEGFR2  
• Gene symbol
  KDR
• Short name
  Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Polyclonal Antibody ( , ),
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rat
• Label
  HRP
• Species
  Pig, Pigs and Guinea pigs, Rats
• Alternative name
  Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) polyclonal (antibody to-) (Rat, swine), horseradish peroxidase
• Alternative technique
  polyclonals, antibodies
• Tissue
  vascular

Gene info

• Identity
  HGNC:6307
• Gene
  KDR
• Long gene name
  kinase insert domain receptor
• Synonyms gene name
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
• Synonyms
  • FLK1
  • VEGFR
  • VEGFR2
  • CD309
• Synonyms name
  • vascular endothelial growth factor receptor 2
  • fetal liver kinase 1
• GenBank acession
  • AF035121
• Locus
  4q12
• Discovery year
  1991-07-10
• Entrez gene record
  3791
• Pubmed identfication
  • 1417831
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • I-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000128734
• Locus Specific Databases
  • The Globin Gene Server
  • LRG_1198

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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