Keratin-8, human recombinant

  • Catalog number
    4817-5
  • Price
    Please ask
  • Size
    5 ug
  • Synonyms
    Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, KRT8, CYK8, KO, CK8, K2C8, CARD2,
  • Alternative_names
    Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, KRT8, CYK8, KO, CK8, K2C8, CARD2,
  • Description
    Key structural material in skin, hair and nails
  • Recombinant
    Yes
  • Source
    E. coli
  • Purity by SDS PAGE
    ≥90%
  • Assay
    SDS-PAGE
  • Purity
    ≥90%
  • Molecular Weight
    78.0 kDa
  • Storage Temp
    -20°C
  • Shipping
    Blue ice
  • Shelf Life
    12 months
  • Concentration
    0.1 ug/ul
  • Appearance
    Liquid
  • Physical form description
    Sterile filtered (5 ug/50 ul) in Tris-Acetate (pH 7.5), 1 mM EDTA, 20% glycerol.
  • Background Information
    Keratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. Keratin 8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. HepatoCellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18. The recombinant human keratin-8 is expressed in E. coli and purified by proprietary chromatographic techniques.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    KRT8P11, KRTAP10-8, KRT8P12
  • Short name
    Keratin-8, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    Keratin-8, H. sapiens Rec.
  • Alternative technique
    rec
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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