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Crizotinib for cell activation

Crizotinib for cell activation is available 0 time from Biovision labs

Description A specific, ATP-competitive, small-molecule inhibitor of the receptor tyrosine kinases (RTKs) c-Met and anaplastic lymphoma kinase (ALK). Iinhibits tyrosine phosphorylation of activated ALK at nanomolar concentrations. Inhibits the growth and survival of cell lines dependent upon c-Met or ALK enzymatic activity.
Peptide sequence N/A
CAS number 877399-52-5
Molecular weight 450.34
Category Biochemicals
Other name 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
Molecular formula C₂₁H₂₂Cl₂FN₅O
Physical appearance Off-white solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Reconstitute instructions DMSO
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 36 months
Storage instructions Protect from air and light
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetCrizotinib for activation
Short name Crizotinib for activation
Technique activation
Alternative name Crizotinib to measure cellular activation
Tissue cell
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