Mouse anti MAPK3 (Mitogen-activated protein kinase 3 antibody (ERK1)

• Catalog number
  X2675M
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  p44 MAP Kinase (ERK) belongs to the protein kinase superfamily, the MAP kinase subfamily and contains 1 protein kinase domain It is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4)._x000B__x000B_
• Antibody come from
  Synthetic peptide derived from the human GAPDH alpha protein.
• Other description
  Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
• Clone
  E32
• Antigen antibody binding interaction
  Mouse anti MAPK3 (Mitogen-activated protein kinase 3 antibody (ERK1) Antibody
• Antibody is raised in
  Mouse
• Antibody s reacts with
  Human, Mouse
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  WB, IP
• Antibody s suited for
  Antibody can be used for Western Blotting (1:400 dilution) and immunohistochemistry (2-10 µg/ml). Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  1. Nakajima, H., et al. 'GAPDH aggregate formation participates in oxidative stress-induced cell death.' J. Biol. Chem. 2009:Epub_x000B__x000B_2. Nahlik, K.W., et al. 'Modulation of GAPDH expression and cellular localization after vaccinia virus infection of human adherent monocytes.' Acta Biochim. Pol. 2003: 50(3); 667-676.
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  MAPK3   Mitogen-activated   protein   kinase   ERK1  
• Gene symbol
  MAPK3
• Short name
  Mouse anti MAPK3 (Mitogen-activated protein kinase 3 antibody (ERK1)
• Technique
  Antibody, Mouse, anti, antibody to, antibodies against human proteins, antibodies for, mouses
• Host
  mouse
• Isotype
  IgG1
• Label
  unlabeled
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to mitogen-activated protein kinase 3 (Mitogen-activated protein phosphorylation catalyst 3 (antibody to-) (ERK1)
• Alternative technique
  antibodies, murine
• Alternative to gene target
  mitogen-activated protein kinase 3, ERK-1 and ERK1 and ERT2 and HS44KDAP and HUMKER1A and p44-ERK1 and p44-MAPK and P44ERK1 and P44MAPK and PRKM3, MAPK3 and IDBG-25745 and ENSG00000102882 and 5595, transferase activity, nuclei, Mapk3 and IDBG-209781 and ENSMUSG00000063065 and 26417, MAPK3 and IDBG-639178 and ENSBTAG00000016156 and 531391

Gene info

• Identity
  HGNC:6877
• Gene
  MAPK3
• Long gene name
  mitogen-activated protein kinase 3
• Synonyms gene
  • PRKM3
• Synonyms
  • ERK1
  • p44mapk
  • p44erk1
• GenBank acession
  • M84490
• Locus
  16p11.2
• Discovery year
  1993-11-05
• Entrez gene record
  5595
• Pubmed identfication
  • 9628824
• Classification
  • Mitogen-activated protein kinases
• VEGA ID
  OTTHUMG00000132149

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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