CHMP4B+CHMP4C Antibody, ALEXA FLUOR 594
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Catalog numberbs-7744R-A594
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PricePlease ask
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Size100ul
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Long nameCHMP4B+CHMP4C Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
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Also known asAnti-CHMP4B+CHMP4C PAb ALEXA FLUOR 594
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 594
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenCHMP4B+CHMP4C
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SpecificityThis is a highly specific antibody against CHMP4B+CHMP4C.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range95-137/224
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHMP4B/CHMP4C
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Gene ID Number128866, 92421
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Swiss ProtQ9H444, Q96CF2
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenProbable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission590nm/617nm
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SynonymsCHMP4B: Charged multivesicular body protein 4b, Chromatin-modifying protein 4b, CHMP4b, SNF7 homolog associated with Alix 1, SNF7-2, hSnf7-2, Vacuolar protein sorting-associated protein 32-2, Vps32-2, hVps32-2 CHMP4C: Charged multivesicular body protein 4c, Chromatin-modifying protein 4c, CHMP4c, SNF7 homolog associated with Alix 3 SNF7-3, hSnf7-3, Vacuolar protein sorting-associated protein 32-3, Vps32-3, hVps32-3
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PropertiesFor facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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French translationanticorps
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Gene target
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Gene symbolCHMP4C, CHMP4B
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Short nameAnti-CHMP4B+CHMP4C
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameCHMP4B+CHMP4C Polyclonal Antibody, ALEXA FLUOR 594
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecharged multivesicular body protein 4C
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Synonyms gene name
- chromatin modifying protein 4C
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2005-04-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Charged multivesicular body proteins
- ESCRT-III
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecharged multivesicular body protein 4B
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Synonyms gene
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Synonyms gene name
- chromosome 20 open reading frame 178
- chromatin modifying protein 4B
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-07-17
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Entrez gene record
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Pubmed identfication
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Classification
- ESCRT-III
- Charged multivesicular body proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data