SDF-1β/CXCL2, rat recombinant

• Catalog number
  7200-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  Stromal-Cell Derived Factor-1, CXCL12, PBSF
• Alternative_names
  Stromal-Cell Derived Factor-1, CXCL12, PBSF
• Description
  Chemoattracts B and T cells and induces migration of CD34+ stem cells
• Recombinant
  Yes
• Source
  E. Coli
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 0.1 ng/ug of protein (
• Activity Specifications test method
  Determined by its ability to chemoattract human monocytes using a concentration range of 100.0-200.0 ng/ml.
• Biological activity
  Determined by its ability to chemoattract human monocytes using a concentration range of 100.0-200.0 ng/ml.
• Molecular Weight
  8.4 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized powder
• Physical form description
  Sterile filtered through a 0.2 micron filter. Lyophilized with no additives
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
• Background Information
  SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant rat SDF-1β is an 8.4 kDa protein containing 72 amino acid residues.
• Amino acid sequence
  KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  SDF-1β/CXCL2  
• Gene symbol
  CXCL12, SFRP2, CXCL2, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1
• Short name
  SDF-1β/CXCL2, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Rat
• Species
  Rats
• Alternative name
  SDF-1β/chemokine (C-X-C motif) ligand 2, rat Rec.
• Alternative technique
  rec
• Alternative to gene target
  chemokine (C-X-C motif) ligand 2, CINC-2a and GRO2 and GROb and MGSA-b and MIP-2a and MIP2 and MIP2A and SCYB2, CXCL2 and IDBG-24257 and ENSG00000081041 and 2920, chemokine activity, Extracellular

Gene info

• Identity
  HGNC:10672
• Gene
  CXCL12
• Long gene name
  C-X-C motif chemokine ligand 12
• Synonyms gene
  • SDF1A
  • SDF1B
  • SDF1
• Synonyms gene name
  • stromal cell-derived factor 1
  • chemokine (C-X-C motif) ligand 12
• Synonyms
  • SCYB12
  • SDF-1a
  • SDF-1b
  • PBSF
  • TLSF-a
  • TLSF-b
  • TPAR1
• GenBank acession
  • L36033
• Locus
  10q11.21
• Discovery year
  1994-11-30
• Entrez gene record
  6387
• Pubmed identfication
  • 7490086
• RefSeq identity
  • NM_000609
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000018054

Gene info

• Identity
  HGNC:10777
• Gene
  SFRP2
• Long gene name
  secreted frizzled related protein 2
• Synonyms
  • SARP1
  • SDF-5
  • FRP-2
• GenBank acession
  • AF017986
• Locus
  4q31.3
• Discovery year
  1998-07-15
• Entrez gene record
  6423
• Pubmed identfication
  • 9391078
• Classification
  • Secreted frizzled-related proteins
• VEGA ID
  OTTHUMG00000161559

Gene info

• Identity
  HGNC:4603
• Gene
  CXCL2
• Long gene name
  C-X-C motif chemokine ligand 2
• Synonyms gene
  • GRO2
• Synonyms gene name
  • GRO2 oncogene
  • chemokine (C-X-C motif) ligand 2
• Synonyms
  • SCYB2
  • GROb
  • MIP-2a
  • MGSA-b
  • CINC-2a
• GenBank acession
  • M36820
• Locus
  4q13.3
• Discovery year
  1991-05-21
• Entrez gene record
  2920
• Pubmed identfication
  • 2217207
• RefSeq identity
  • NM_002089
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000160865

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

Gene info

• Identity
  HGNC:31488
• Gene
  MIR101-1
• Long gene name
  microRNA 101-1
• Synonyms gene
  • MIRN101-1
• Synonyms
  • hsa-mir-101-1
• Locus
  1p31.3
• Discovery year
  2004-04-23
• Entrez gene record
  406893
• RefSeq identity
  • NR_029516
• Classification
  • MicroRNA MIR101 family

Gene info

• Identity
  HGNC:35281
• Gene
  MIR1289-1
• Long gene name
  microRNA 1289-1
• Synonyms gene
  • MIRN1289-1
• Synonyms
  • hsa-mir-1289-1
• Locus
  20q11.22
• Discovery year
  2008-11-03
• Entrez gene record
  100302125
• RefSeq identity
  • NR_031620
• Classification
  • MicroRNA MIR1289 family

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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