NGF-beta, murine recombinant
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Catalog number
4304-1000
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Price
Please ask
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Size
1 mg
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Synonyms
β Polypeptide, NGF, NGFB, HSAN5, β-NGF, MGC161426, MGC161428.
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Alternative_names
β Polypeptide, NGF, NGFB, HSAN5, β-NGF, MGC161426, MGC161428.
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Description
A factor critical for the survival & maintenance of sympathetic and sensory neurons
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Recombinant
Yes
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Source
E. coli
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Purity by SDS PAGE
≥98%
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Assay
SDS-PAGE
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Purity
≥98%
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Biological activity
This NGF- β is fully biologically active when compared to standards. The ED₅₀ as measured by the dose-dependent induction of human TF-1 cell proliferation is typically 0.1–1 ng/ml
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Results
0.1–1 ng/ml
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Molecular Weight
13.5 kDa
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Storage Temp
-20°C
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Shipping
Gel pack
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Shelf Life
12 months
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Appearance
Lyophilized protein
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Physical form description
Lyophilized with no additives
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Reconstitution Instructions
Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml containing 1% HSA or BSA. The solution can be diluted into other aqueous buffers and stored at 4°C for 2-7 days or store at –20°C for future use.
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Background Information
Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. The active recombinant mouse NGF-β is a homodimer, non-glycosylated chain containing two identical 120 amino acid subunits, and having a molecular weight of 13.5 kDa.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
NGF, NGF-AS1
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Short name
NGF-beta, murine recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative name
nerve growth factor (beta polypeptide)-b, murine Rec.
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Alternative technique
rec
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Alternative to gene target
nerve growth factor (beta polypeptide), Beta-NGF and HSAN5 and NGFB, NGF and IDBG-101347 and ENSG00000134259 and 4803, growth factor activity, Extracellular, Ngf and IDBG-180362 and ENSMUSG00000027859 and 18049, NGF and IDBG-648895 and ENSBTAG00000007446 and 281350
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Gene info
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Identity
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Gene
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Long gene name
nerve growth factor
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Synonyms gene
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Synonyms gene name
- nerve growth factor (beta polypeptide)
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
NGF antisense RNA 1
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Synonyms
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Locus
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Discovery year
2018-06-08
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Pubmed identfication
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Classification
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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