Integrin alphaM (Itgam, CD11b/CD18, CD11B (p170), CD11b Antigen, Cell Surface Glycoprotein MAC-1 alpha Subunit, Complement Component Receptor 3 alpha-a (CR3A), Complement Receptor Type 3, CR3, CR3A, CR-3 alpha Chain, F730045J24Rik, Integrin alpha-M Precur[Integrin alphaM]

• Catalog number
  MBS611650
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human, Mouse
• Description
  The Integrin alphaM (Itgam, CD11b/CD18, CD11B (p170), CD11b Antigen, Surface Glycoprotein MAC-1 alpha Subunit, Complement Component Receptor 3 alpha-a (CR3A), Complement Receptor 3, CR3, CR3A, CR-3 alpha Chain, F730045J24Rik, Integrin alpha-M Precur[Integrin alphaM] is a α- or alpha protein sometimes glycoprotein present in blood. Antigens are peptides or recombinant or native dependent on the production method. For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Integrin   alphaM   Itgam   CD11b/CD18   CD11B   p170   CD11b   Surface   Glycoprotein   MAC-1   alpha   Subunit   Complement   Component   Receptor   alpha-a   CR3A   Complement   Receptor   CR3   CR3A   CR-3   alpha   Chain   F730045J24Rik   Integrin   alpha-M   Precur[Integrin   alphaM]  
• Gene symbol
  ITGAM, ITGB2, TDGF1, TDGF1P3, LGALS3, YWHAZ, CD55, TRR-CCG1-3, TRR-ACG1-3, TRW-CCA3-3
• Short name
  Integrin alphaM (Itgam, CD11b/CD18, CD11B (p170), CD11b Antigen, Surface Glycoprotein MAC-1 alpha Subunit, Complement Component Receptor 3 alpha-a (CR3A), Complement Receptor 3, CR3, CR3A, CR-3 alpha Chain, F730045J24Rik, Integrin alpha-M Precur[Integrin alphaM]
• Technique
  antigen, antigenes
• Host
  Rabbit
• Alternative name
  Integrin alphaM (integrin, alpha M (complement component 3 receptor 3 subunit), CD11b/CD18, CD11B (p170), CD11b protein, cellular Surface Glycoprotein MAC-1 a functionnal sequence, Complement Component Receptor 3 a-a (CR3A), Complement Receptor classification 3, CR3, CR3A, CR-3 a epitope, F730045J24Rik, Integrin a-M Precur[Integrin alphaM]
• Alternative technique
  antigenes
• Alternative to gene target
  integrin, alpha M (complement component 3 receptor 3 subunit), CD11B and CR3A and MAC-1 and MAC1A and MO1A and SLEB6, ITGAM and IDBG-28139 and ENSG00000169896 and 3684, protein heterodimerization activity, nuclei, Itgam and IDBG-210531 and ENSMUSG00000030786 and 16409, BT.35830 and IDBG-639593 and ENSBTAG00000047238 and 407124
• Tissue
  cell

Gene info

• Identity
  HGNC:6149
• Gene
  ITGAM
• Long gene name
  integrin subunit alpha M
• Synonyms gene
  • CR3A
  • CD11B
• Synonyms gene name
  • integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide)
  • integrin, alpha M (complement component 3 receptor 3 subunit)
• Synonyms
  • MAC-1
  • CD11b
• Synonyms name
  • complement component 3 receptor 3 subunit
  • macrophage-1 antigen alpha subunit
• GenBank acession
  • J03925
• Locus
  16p11.2
• Discovery year
  1988-08-05
• Entrez gene record
  3684
• RefSeq identity
  • NM_000632
• Classification
  • Integrin alpha subunits
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000176612
• Locus Specific Databases
  • LRG_1333

Gene info

• Identity
  HGNC:6155
• Gene
  ITGB2
• Long gene name
  integrin subunit beta 2
• Synonyms gene
  • CD18
  • MFI7
• Synonyms gene name
  • integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
• Synonyms
  • LFA-1
  • MAC-1
• Synonyms name
  • complement component 3 receptor 3 and 4 subunit
• GenBank acession
  • AK222505
• Locus
  21q22.3
• Discovery year
  1986-01-01
• Entrez gene record
  3689
• RefSeq identity
  • NM_000211
• Classification
  • Integrin beta subunits
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000090257
• Locus Specific Databases
  • ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I)
  • LRG_76

Gene info

• Identity
  HGNC:11701
• Gene
  TDGF1
• Long gene name
  teratocarcinoma-derived growth factor 1
• Synonyms
  • CRIPTO
  • CR
  • Cripto-1
  • CR-1
• GenBank acession
  • M96955
• Locus
  3p21.31
• Discovery year
  1990-08-02
• Entrez gene record
  6997
• Pubmed identfication
  • 1882841
  • 10393436
• RefSeq identity
  • NM_003212
• VEGA ID
  OTTHUMG00000191980

Gene info

• Identity
  HGNC:11703
• Gene
  TDGF1P3
• Long gene name
  teratocarcinoma-derived growth factor 1 pseudogene 3
• Synonyms gene
  • TDGF3
• Synonyms gene name
  • teratocarcinoma-derived growth factor 3, pseudogene
• Synonyms
  • TDGF2
  • CR-3
  • CRIPTO-3
  • CRIPTO3
• GenBank acession
  • M96956
• Locus
  Xq23
• Discovery year
  1990-08-02
• Entrez gene record
  6998
• Pubmed identfication
  • 1882841
• RefSeq identity
  • NR_002718
• VEGA ID
  OTTHUMG00000022195

Gene info

• Identity
  HGNC:6563
• Gene
  LGALS3
• Long gene name
  galectin 3
• Synonyms gene
  • LGALS2
• Synonyms gene name
  • lectin, galactoside-binding, soluble, 3
• Synonyms
  • MAC-2
  • GALIG
• Synonyms name
  • advanced glycation end-product receptor 3
• GenBank acession
  • M64303
• Locus
  14q22.3
• Discovery year
  1991-09-13
• Entrez gene record
  3958
• Pubmed identfication
  • 2009535
  • 8063692
• RefSeq identity
  • NM_002306
• Classification
  • Receptor ligands
  • Galectins
• VEGA ID
  OTTHUMG00000171030

Gene info

• Identity
  HGNC:12855
• Gene
  YWHAZ
• Long gene name
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
• Synonyms gene
  • YWHAD
• Synonyms gene name
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
• Synonyms
  • KCIP-1
  • 14-3-3-zeta
• Synonyms name
  • 14-3-3 zeta
  • 14-3-3 delta
• GenBank acession
  • U28964
• Locus
  8q22.3
• Discovery year
  1993-09-20
• Entrez gene record
  7534
• Pubmed identfication
  • 8617504
  • 7890696
• RefSeq identity
  • NM_145690
• Classification
  • 14-3-3 phospho-serine/phospho-threonine binding proteins
• VEGA ID
  OTTHUMG00000134291

Gene info

• Identity
  HGNC:2665
• Gene
  CD55
• Long gene name
  CD55 molecule (Cromer blood group)
• Synonyms gene
  • DAF
• Synonyms gene name
  • decay accelerating factor for complement (CD55, Cromer blood group system)
  • CD55 molecule, decay accelerating factor for complement (Cromer blood group)
• Synonyms
  • CR
  • TC
  • CROM
• GenBank acession
  • BC001288
• Locus
  1q32.2
• Discovery year
  2001-06-22
• Entrez gene record
  1604
• RefSeq identity
  • NM_000574
• Classification
  • Blood group antigens
  • Complement system regulators and receptors
  • CD molecules
  • Sushi domain containing
• VEGA ID
  OTTHUMG00000036255
• Locus Specific Databases
  • Blood Group Antigen Mutation Database
  • CD55base: Mutation registry for Decay-accelerating factor (CD55) deficiency (previously known as DAFbase)
  • LRG_127

Gene info

• Identity
  HGNC:34735
• Gene
  TRR-CCG1-3
• Long gene name
  tRNA-Arg (anticodon CCG) 1-3
• Synonyms gene
  • TRNAR19
  • TRR-CCG1-1
• Synonyms gene name
  • transfer RNA arginine 19 (anticodon CCG)
  • transfer RNA-Arg (CCG) 1-1
  • transfer RNA-Arg (CCG) 1-3
• Synonyms
  • tRNA-Arg-CCG-1-3
• GenBank acession
  • HG983601
• Locus
  16p13.3
• Discovery year
  2008-08-29
• Entrez gene record
  100189173
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34806
• Gene
  TRR-ACG1-3
• Long gene name
  tRNA-Arg (anticodon ACG) 1-3
• Synonyms gene
  • TRNAR21
  • TRR-ACG1-1
• Synonyms gene name
  • transfer RNA arginine 21 (anticodon ACG)
  • transfer RNA-Arg (ACG) 1-1
  • transfer RNA-Arg (ACG) 1-3
• Synonyms
  • tRNA-Arg-ACG-1-3
• GenBank acession
  • HG983594
• Locus
  14q11.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189243
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34674
• Gene
  TRW-CCA3-3
• Long gene name
  tRNA-Trp (anticodon CCA) 3-3
• Synonyms gene
  • TRNAW3
  • TRW-CCA3-1
• Synonyms gene name
  • transfer RNA tryptophan 3 (anticodon CCA)
  • transfer RNA-Trp (CCA) 3-1
  • transfer RNA-Trp (CCA) 3-3
• Synonyms
  • tRNA-Trp-CCA-3-3
• GenBank acession
  • HG984066
• Locus
  17p13.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189112
• Classification
  • Cytoplasmic transfer RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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