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CLN8 Antibody, Cy7 Conjugated

CLN8 Antibody, Cy7 Conjugated is available 1 time from Bioss primary conjugated antibodies labs

bs-11715R-Cy7 | CLN8 Antibody, Cy7 Conjugated size: 0.1ml | 407.93 USD

Catalog number bs-11715R-Cy7
Price 407.93 USD
Size 0.1ml
1. Gene info
Identity 2079
Gene CLN8
Long gene name CLN8 transmembrane ER and ERGIC protein
Synonyms gene
  • EPMR
  • C8orf61
Synonyms gene name
  • chromosome 8 open reading frame 61
  • epilepsy, progressive with mental retardation
  • ceroid-lipofuscinosis, neuronal 8
  • CLN8, transmembrane ER and ERGIC protein
Synonyms
  • FLJ39417
  • TLCD6
GenBank acession
  • AF123761
Locus 8p23.3
Discovery year 1993-12-15
Entrez gene record 2055
Pubmed identfication
  • 10508524
  • 23160995
RefSeq identity
  • NM_018941
Classification
  • TLC domain containing
Havana BLAST/BLAT OTTHUMG00000090343
Locus Specific Databases
  • Neuronal Ceroid Lipofuscinoses; NCL Mutations
  • LRG_691
Product images
    #ntibody#.jpg#.pngParaformaldehyde-fixed, paraffin embedded rat brain; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes;  Blocking buffer (normal goat serum) at 37\u00b0C for 20miHela cell lysates probed with CLN8 Polyclonal Antibody, Unconjugated (bs-11715R) at 1:1000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.
Product files
Long name CLN8 Polyclonal Antibody, Cy7 Conjugated
Category Conjugated Primary Antibodies
Conjugation Cy7
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen CLN8
Specificity This is a highly specific antibody against CLN8.
Modification Unmodified
Modification site None
Clonality Polyclonal
Clone Polyclonal antibody
Concentration 1ug per 1ul
Source KLH conjugated synthetic peptide derived from human CLN8
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Crossreactivity Human, Mouse, Rat
Crossreactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Antigen background CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
Purification method This antibody was purified via Protein A.
Storage conditions Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Excitation Emission 743nm/767nm
Synonyms Ceroid-lipofuscinosis, neuronal 8 epilepsy, progressive with mental retardation; Cln8; CLN8_HUMAN; EPMR; Protein CLN8.
Properties If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugated These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
Additional conjugation Cy7
French translation anticorps
Gene targetCLN8 Conjugated
Short name Anti-CLN8
Technique Antibody
Isotype Immunoglobulin G (IgG)
Label Cy7
Alternative name Anti-CLN8 PAb Cy7
Alternative technique antibodies
Alternative to gene target ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation), C8orf61 and EPMR, CLN8 and IDBG-5421 and ENSG00000182372 and 2055, Plasma membranes, Cln8 and IDBG-136384 and ENSMUSG00000026317 and 26889, CLN8 and IDBG-628376 and ENSBTAG00000008584 and 530874
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Anti-CLN8 | Technique alternative | 01010257710
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  • CLN8
  • Conjugated
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