CLN8 Antibody, Cy7 Conjugated
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Catalog number
bs-11715R-Cy7
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Price
Please ask
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Size
0.1ml
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Long name
CLN8 Polyclonal Antibody, Cy7 Conjugated
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Category
Conjugated Primary Antibodies
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Conjugation
Cy7
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
CLN8
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Specificity
This is a highly specific antibody against CLN8.
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Modification
Unmodified
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Modification site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic peptide derived from human CLN8
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen background
CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission
743nm/767nm
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Synonyms
Ceroid-lipofuscinosis, neuronal 8 epilepsy, progressive with mental retardation; Cln8; CLN8_HUMAN; EPMR; Protein CLN8.
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Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugated
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
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Additional conjugation
Cy7
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French translation
anticorps
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Gene target
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Gene symbol
CLN8-AS1, CLN8
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Short name
Anti-CLN8
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Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
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Isotype
Immunoglobulin G (IgG)
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Label
Cy7
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Alternative name
Anti-CLN8 PAb Cy7
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Alternative technique
antibodies
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Alternative to gene target
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation), C8orf61 and EPMR, CLN8 and IDBG-5421 and ENSG00000182372 and 2055, Plasma membranes, Cln8 and IDBG-136384 and ENSMUSG00000026317 and 26889, CLN8 and IDBG-628376 and ENSBTAG00000008584 and 530874
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Gene info
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Identity
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Gene
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Long gene name
CLN8 antisense RNA 1
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Locus
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Discovery year
2021-03-18
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Entrez gene record
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RefSeq identity
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Classification
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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