Purified GST-tagged human RAR-related orphan receptor alpha ligand binding domain

  • Catalog number
    N1F1-50
  • Price
    Please ask
  • Size
    50 μg
  • Description
    Purified GST-tagged human RAR-related orphan receptor alpha ligand binding domain is used mainly for ligand-binding and coregulator displacement assays
  • Produced in
    NA
  • Application
    Drug discovery, Nuclear receptors, purified recombinant protein
  • Gene number
    6095
  • Delivery
    Shipped under dry ice. Additional shipping fee will be made.
  • Storage
    Store at minus 80°C
  • Technical file
    Please inquire the latest datasheet, protocol, certificate of analysis or SDS
  • Additional description
    The RORA-LBD is a α- or alpha protein sometimes glycoprotein present in blood. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Gene target
  • Gene symbol
    RARA, MGST3, RAB40B, PRAM1, RAB40A
  • Short name
    RORA-LBD
  • Technique
    purified, purifications
  • Species
    Human, Humans
  • Alternative name
    enriched GST-tagged H. sapiens RAR-related orphan receptor a ligand binding domain
  • Alternative technique
    pure
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