Recombinant Human IL-2RA/CD25 (C-hFc)

Alternative names

Interleukin-2 receptor subunit alpha;CD25;p55;TAC antigen;IL2-RA;IL-2R subunit alpha;IL-2-RA;IL-2 receptor subunit alpha;IL-2 R alpha
Description

Recombinant Human Interleukin-2 Receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu22-Cys213 is expressed with a Fc tag at the C-terminus.
Expression

Human 293 Cells
Tag

C-hFc
Endotoxin

Less than 0.1 EU/ug
Accession

P01589
TargetSequence

Glu22-Cys213
Shipping

Ambient
Formulation

Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Note

For research use only.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

IL-2RA/CD25 C-hFc
Gene symbol

IL2RA, ISG20, IL36G, IL25, IL22, IL18, IL37, IL6R, IL17C, IL17D
Short name

Recombinant IL-2RA/CD25 (C-hFc)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens Interleukin-2RA/CD25 (C-hFc)
Alternative technique

rec

Identity

HGNC:6008
Gene

IL2RA
Long gene name

interleukin 2 receptor subunit alpha
Synonyms gene
- IL2R
- IDDM10
Synonyms gene name
- insulin-dependent diabetes mellitus 10
- interleukin 2 receptor, alpha
Synonyms
- CD25
GenBank acession
- X01057
Locus

10p15.1
Discovery year

1990-01-22
Entrez gene record

3559
Pubmed identfication
- 3925551
- 17676041
RefSeq identity
- NM_000417
Classification
- CD molecules
- Sushi domain containing
- Interleukin receptors
VEGA ID

OTTHUMG00000017616
Locus Specific Databases
- IL2RAbase: Mutation registry for Interleuken 2 receptor α deficiency
- LRG_73

Identity

HGNC:6019
Gene

IL6R
Long gene name

interleukin 6 receptor
Synonyms
- CD126
- IL-6R
- IL-1Ra
- IL6RA
- gp80
Synonyms name
- membrane glycoprotein 80
- interleukin 6 receptor subunit alpha
GenBank acession
- X12830
Locus

1q21.3
Discovery year

2001-06-22
Entrez gene record

3570
Pubmed identfication
- 8428753
- 12633863
RefSeq identity
- NM_000565
Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000036073

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data