Anti-PLC gamma 1 (Tyr771) (Polyclonal), ALEXA Fluor 594
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Catalog numberGENTObs-3460R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptidePLC gamma 1 Tyr771
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SpecificityThis antibody reacts specifically with PLC gamma 1 (Tyr771)
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ModificationPhosphorylation
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Modification siteTyr771
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsN/A
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Antigen SourceKLH conjugated synthetic phosphopeptide derived from human PLC gamma 1 around the phosphorylation site of Tyr771
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Gene ID5335
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Swiss ProtN/A
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ApplicationsIF(IHC-P)
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Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
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Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationThe protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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SynonymsPLC 1; PLC 148; PLC gamma 1; PLC II; PLC1; PLC148; PLCG 1; PLCG1; PLCgamma1; PLCII; triphosphoinositide phosphodiesterase; 1 phosphatidyl D myo inositol 4 5 bisphosphate; 1 phosphatidylinositol 4 5 bisphosphate; 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; phosphatidylinositol phospholipase C; phosphodiesterase gamma 1; phosphoinositidase C; phosphoinositide phospholipase C; Phospholipase C 148; phospholipase C gamma 1 formerly subtype 148; Phospholipase C gamma 1; phospholipase C-148; PLCG1_HUMAN.
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Also known asPLC gamma 1 (Tyr771) Polyclonal Antibody
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Other nameAnti-PLC gamma 1 (Tyr771) Polyclonal
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Gene target
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Gene symbolPLCB1, PLCL1, PLCG1, PLCH2, PDIA3
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Short nameAnti-PLC gamma 1 (Tyr771)
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TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative namePLC gamma 1 (Tyr771) Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniquepolyclonals, antibodies
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Gene info
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Identity
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Gene
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Long gene namephospholipase C beta 1
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Synonyms gene name
- phospholipase C, beta 1 (phosphoinositide-specific)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-21
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Entrez gene record
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Pubmed identfication
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Classification
- Phospholipases
- C2 domain containing phospholipases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephospholipase C like 1 (inactive)
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Synonyms gene
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Synonyms gene name
- phospholipase C, epsilon
- phospholipase C-like 1
- phospholipase C like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-12-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein phosphatase 1 regulatory subunits
- C2 domain containing phospholipases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephospholipase C gamma 1
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Synonyms gene
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Synonyms gene name
- phospholipase C, gamma 1 (formerly subtype 148)
- phospholipase C, gamma 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-05-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
- MicroRNA protein coding host genes
- Phospholipases
- SH2 domain containing
- C2 domain containing phospholipases
- EF-hand domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephospholipase C eta 2
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Synonyms gene
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Synonyms gene name
- phospholipase C-like 4
- phospholipase C, eta 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-07-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EF-hand domain containing
- Phospholipases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein disulfide isomerase family A member 3
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Synonyms gene
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Synonyms gene name
- glucose regulated protein, 58kDa
- protein disulfide isomerase-associated 3
- protein disulfide isomerase family A, member 3
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Synonyms
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Locus
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Discovery year1997-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein disulfide isomerases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
