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Anti- Neuropilin-1 (Polyclonal), ALEXA Fluor 594

Anti- Neuropilin-1 (Polyclonal), ALEXA Fluor 594 is available 1 time from Bioss polyclonal antibodies labs

GENTObs-0693R-A594 | Anti- Neuropilin-1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters | 583.67 USD

Catalog number GENTObs-0693R-A594
Price 583.67 USD
Size 100 microliters
1. Gene info
Identity 13823
Gene NETO1
Long gene name neuropilin and tolloid like 1
Synonyms gene name
  • neuropilin (NRP) and tolloid (TLL)-like 1
Synonyms
  • BTCL1
  • BCTL1
GenBank acession
  • AF448838
Locus 18q22.3
Discovery year 2001-04-05
Entrez gene record 81832
Pubmed identfication
  • 11943477
  • 12810072
RefSeq identity
  • NM_138999
Classification
  • MicroRNA protein coding host genes
Havana BLAST/BLAT OTTHUMG00000132834
Product images
    Formalin-fixed and paraffin embedded rat small intestine labeled Anti-NRP1/CD304 Polyclonal Antibody, Unconjugated (bs-0693R) at 1:200, followed by conjugation to the secondary antibody and DAB staining
Type Conjugated Primary Antibody
Conjugated with ALEXA FLUOR® 594
Host organism Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide Neuropilin 1
Specificity This antibody reacts specifically with Neuropilin-1
Modification No modification has been applied to this antibody
Modification site None
Clonality Polyclonal Antibody
Clone Polyclonal Antibodies
Concentration 1ug per 1ul
Subcellular locations Cytoplasm
Antigen Source KLH conjugated synthetic peptide derived from human neuropilin-1
Gene ID 8829
Swiss Prot O14786
Applications IF(IHC-P)
Applications with corresponding dilutions IF(IHC-P)(1:50-200)
Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Background information The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
Purification method Purified by Protein A.
Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission 590nm/617nm
Synonyms NP1; NRP; BDCA4; CD304; VEGF165R; Neuropilin-1; Vascular endothelial cell growth factor 165 receptor; NRP1
Also known as Neuropilin-1 Polyclonal Antibody
Other name Anti- Neuropilin-1 Polyclonal
Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Properties For facs or microscopy Alexa 1 conjugate.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Gene targetNeuropilin-1
Short name Anti- Neuropilin-1
Technique Polyclonal, anti-, anti
Isotype Immunoglobulin G (IgG)
Label ALEXA FLUOR 594
Alternative name Neuropilin-1 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
Alternative technique polyclonals
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Anti- Neuropilin-1 | Technique alternative | 01011204440
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