Alpha 2 HS Glycoprotein Antibody

• Catalog number
  A1111-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  AHSG
• Target Alternative Name
  Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Human alpha 2 SH Glycoprotein (Cat. No. 7548)
• Accession
  P02765
• Gene Id
  197
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  In PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin® and 50 % glycerol
• Purification
  Affinity purified rabbit IgG
• Application
  WB
• Positive Control
  WB: h serum, h alpha 2 HS Glycoprotein
• Application And Usages
  WB: 1-4 µg
• Description
  Alpha 2 macroglobulin (A2M) is a major serum protein found at concentrations of 240 mg per 100 ml in men and 290 mg per 100 ml in women. It functions as a broad-spectrum protease-binding protein. It is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis. It is a large plasma glycoprotein that has long been known as an irreversible inhibitor of a variety of proteinases. More recently, it has been reported that numerous growth factors, cytokines and hormones bind to alpha 2M through diverse mechanisms. A2M is also produced in the brain where it binds multiple extracellular ligands and is internalized by neurons and astrocytes. In the brain of Alzheimer's disease (AD) patients, A2M has been localized to diffuse amyloid plaques. A2M also binds soluble beta-amyloid, of which it mediates degradation. Protease-conjugated alpha2-macroglobulin is selectively bound by cells contacting the body fluids and alpha2-macroglobulin and its protease cargo are then internalized and degraded in secondary lysosomes of those cells.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  The Alpha 2 HS Glycoprotein Antibody is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Alpha   Glycoprotein  
• Gene symbol
  AHSG
• Short name
  Alpha 2 HS Glycoprotein Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  a 2 HS Glycoprotein (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:349
• Gene
  AHSG
• Long gene name
  alpha 2-HS glycoprotein
• Synonyms
  • FETUA
  • A2HS
  • HSGA
• Synonyms name
  • fetuin A
• GenBank acession
  • D67013
  • M16961
• Locus
  3q27.3
• Discovery year
  1986-01-01
• Entrez gene record
  197
• Pubmed identfication
  • 9322749
  • 7736783
• RefSeq identity
  • NM_001622
• Classification
  • Cystatins, type 4
• VEGA ID
  OTTHUMG00000156605

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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