TrkA Antibody

• Catalog number
  3194-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  TrkA
• Target Alternative Name
  Trk-A, TRK1 , NTRK1, TRK, CIPA
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 494 of human TrkA
• Accession
  BAA34355
• Gene Id
  4914
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit anti-TrkA polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Immunoprecipitation, Immunohistochemistry
• Application And Usages
  Western blotting (0.5-4 µg/ml) in immunoprecipitation, and Immunohistochemistry. However, the optimal conditions should be determined individually. The antibody detects ~140 kDa TrkA. It does not cross-react with TrkB or TrkC.
• Description
  TrkA, the high affinity Nerve Growth Factor (NGF) receptor, autophosphorylates on tyrosine to activate multiple effectors. Phosphorylation at Tyr490 is required for Shc association and activation of the Ras-MAP kinase cascade. Residues Tyr674/675 lie within the catalytic domain, and phosphorylation at these sites reflects Trk kinase activity.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TrkA  
• Gene symbol
  NTRK1
• Short name
  TrkA Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  TrkA (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8031
• Gene
  NTRK1
• Long gene name
  neurotrophic receptor tyrosine kinase 1
• Synonyms gene name
  • neurotrophic tyrosine kinase, receptor, type 1
• Synonyms
  • TRK
  • TRKA
  • MTC
• Synonyms name
  • high affinity nerve growth factor receptor
• GenBank acession
  • Y09028
• Locus
  1q23.1
• Discovery year
  1991-07-18
• Entrez gene record
  4914
• Pubmed identfication
  • 2869410
• RefSeq identity
  • NM_002529
• Classification
  • Immunoglobulin like domain containing
  • Receptor tyrosine kinases
• VEGA ID
  OTTHUMG00000041304
• Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • LRG_261

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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