ACC2 Inhibitor

  • Catalog number
    1717-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    N-(1-(2’-(4-Isopropoxyphenoxy)-2,5’-bithiazol-5-yl)ethyl)acetamide
  • Description
    Cell-permeable. A potent and selective inhibitor of ACC2 (Acetyl-CoA Carboxylase) (IC₅₀ = 28 nM for hACC2 vs 210 nM for hACC1 in in vitro studies).
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₉H₂₁N₃O₃S₂
  • Molecular Weight
    403.52
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A selective inhibitor of ACC2
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • SMILES
    CC(C)OC(C=C1)=CC=C1OC2=NC=C(C(S3)=NC=C3C(C)NC(C)=O)S2
  • InChi
    InChI=1S/C19H21N3O3S2/c1-11(2)24-14-5-7-15(8-6-14)25-19-21-10-17(27-19)18-20-9-16(26-18)12(3)22-13(4)23/h5-12H,1-4H3,(H,22,23)
  • InChi Key
    CVAJIWQTUPPAIF-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Additional description
    Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
  • Gene target
    ACC2   Inhibitor  
  • Gene symbol
    ACACB, BCL2A1
  • Short name
    ACC2 Inhibitor
  • Alternative name
    ACC2 suppressor
Gene info
Gene info
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