Suramin Hexasodium Salt

  • Catalog number
    1874-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
  • Description
    A P2x and P2y purinergic receptor antagonist that displays antitumor, antiangiogenic and antiparasitic activities. Inhibits sirtuin 1, sirtuin 5 and topoisomerase II. Inhibits the cell surface binding of various growth factors including PDGF, EGF, FGFa and FGFb. Blocks association of G protein α and β/γ-subunits. Potent competitive inhibitor of reverse transcriptase and protects T lymphocytes against in vitro human immunodeficiency virus infection.
  • CAS Number
    129-46-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₅₁H₃₄N₆Na₆O₂₃S₆
  • Molecular Weight
    1429.15
  • Cell Permeable
    No
  • Purity
    ≥98%
  • Solubilities
    DMSO (10 mM) and water (50 mM)
  • Handling
    Protect from air and moisture
  • Tag Line
    A P2x and P2y purinergic receptor antagonist
  • Storage Condition
    +4°C
  • Shipping Condition
    RT
  • Shelf Life
    36 months
  • MDL Number
    MFCD00210217
  • PubChem CID
    8514
  • SMILES
    CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
  • InChi
    InChI=1S/C51H40N6O23S6.6Na/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80;;;;;;/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80);;;;;;/q;6*+1/p-6
  • InChi Key
    VAPNKLKDKUDFHK-UHFFFAOYSA-H
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Suramin Hexasodium Salt
  • Alternative name
    Suramin Hexasodium Salt
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