Rabbit Anti Human POLH Antibody-HRP
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Catalog numberCSB-PA018321LB01HU_100ug
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PricePlease ask
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Size100ug
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Long nameRabbit Antibody against Human POLH, HRP
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Synonym namePOLH Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA
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ConjugationHRP
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Antibody isotypeIgG
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UniProt IDQ9Y253
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant Human DNA polymerase eta protein (408-609AA)
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Immunogen speciesHuman
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AliasDNA polymerase eta,RAD30 homolog A,Xeroderma pigmentosum variant type protein,POLH,RAD30,RAD30A,XPV
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BackgroundDNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
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ClonalityPolyclonal antibody
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Shipping and storagePOLH Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenDNA polymerase eta
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional conjugationHRP Conjugated
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolPOLQ, POLH-AS1, POLH
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Short nameAnti-POLH
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
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HostRabbit, Rabbits
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LabelHRP
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SpeciesHuman, Humans
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Alternative namePOLH Antibody,HRP conjugated
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Alternative techniqueantibodies, rabbit-anti
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Gene info
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Identity
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Gene
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Long gene nameDNA polymerase theta
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Synonyms gene name
- polymerase (DNA directed), theta
- polymerase (DNA) theta
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-04-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- DNA polymerases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePOLH antisense RNA 1
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Synonyms
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Locus
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Discovery year2017-08-30
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Pubmed identfication
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameDNA polymerase eta
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Synonyms gene name
- polymerase (DNA directed), eta
- polymerase (DNA) eta
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-09-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- DNA polymerases
- Xeroderma pigmentosum complementation groups
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data