Human CellExp™ Coronavirus Spike Protein (SARS-CoV-2; S1), Recombinant
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Catalog number
P1524-10
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Price
Please ask
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Size
10 µg
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Description
Glycoprotein that enables viral entry into the host cell
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Recombinant
1
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Source
Mammalian Cell
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Purity by SDS PAGE
>95%
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Storage Temp
-80°C
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Shipping
Dry Ice
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Shelf Life
12 months
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Appearance
Sterile Filtered colorless solution
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Physical form description
Liquid
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Background Information
SARS-CoV is an enveloped, single and positive-stranded RNA virus. Cell entry of severe acute respiratory syndrome coronavirus (SARS-CoV) is mediated by the viral spike (S) protein. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. For viral entry, the surface unit (S1) of SARS S binds to the cellular receptor angiotensin converting enzyme 2 (ACE2) and the transmembrane unit (S2) then fuses the viral membrane with a host cell membrane. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV. Because the S protein of SARS-CoV is involved in receptor recognition, as well as virus attachment and entry, it represents one of the most important targets for the development of SARS vaccines and therapeutics.
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Amino acid sequence
aa 1-674 (Fc tag)
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
SARS1, SARS2
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Short name
CellExp™ Coronavirus Spike Protein (SARS-CoV-2; S1), Recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Humans
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Alternative name
H. sapiens CellExp™ Coronavirus Spike Protein (SARS-CoV-2; S1), Rec.
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Alternative technique
rec
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Virus
coronavirus
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Gene info
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Identity
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Gene
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Long gene name
seryl-tRNA synthetase 1
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Synonyms gene
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Synonyms gene name
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1995-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Aminoacyl tRNA synthetases, Class II
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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