AG 1478

• Catalog number
  1800-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  4-(3’-Chloroanilino)-6,7-dimethoxyquinazoline; Tyrphostin AG 1478
• Description
  Cell-permeable. A potent EGFR Tyrosine Kinase (TK) inhibitor with an IC₅₀ of 3 nM. Only weakly inhibits PDGFR and HER2-NEU kinases (IC₅₀ >100 µM).
• CAS Number
  175178-82-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₆H₁₄ClN₃O₂
• Molecular Weight
  315.75
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO:Methanol 1:1 v/v (10 mg/ml), Ethanol (10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent EGFR Tyrosine Kinase (TK) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  48 months
• MDL Number
  MFCD00270914
• PubChem CID
  53429216
• PubChem CID Link
• SMILES
  COC1=C(C=C2C(=C1)C(=NC=N2)CC3=CC(=CC=C3)Cl)OC
• InChi
  InChI=1S/C17H15ClN2O2/c1-21-16-8-13-14(7-11-4-3-5-12(18)6-11)19-10-20-15(13)9-17(16)22-2/h3-6,8-10H,7H2,1-2H3
• InChi Key
  DOBKKEHYAFERJH-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  1478  
• Short name
  AG 1478
• Alternative name
  AG 1478

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