Bcl2 Antibody ( Bcl-2-100)

• Catalog number
  MA1004
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Bcl2
• Clonality
  Monoclonal antibody
• Clone
  Bcl-2-100
• Raised in
  mice
• Type of the antibody
  IgG1 monoclonal antibody
• Product form
  freeze-dried
• Reacts with species
  Human
• Analyses
  WB,IHC-P,IHC-F,ICC
• Immunogen
  Synthetic peptide corresponding to residues 41-54 of the bcl-2 protein, conjugated to thyroglobulin.
• Product configuration
  Mouse ascites fluid, 1.2% Na acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
• Purification
  Ascites
• Solubilization
  The powdered antibody should be dissolved in 1ml of PBS buffer to achieve final concentration of 100ug/ml.
• Storage condtions
  Keep the Bcl2 Antibody ( Bcl-2-100)at minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Bcl2 Antibody ( Bcl-2-100) did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Immunoreactive BCL2 protein in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue. Every tumor with molecular-genetic evidence of t(14;18) translocation expressed detectable levels of BCL2 protein, regardless of whether the breakpoint was located in or at a distance from the BCL2 gene. Overexpression of BCL2 blocks the apoptotic death of a pro-B-lymphocyte cell line.
• Related articles
  1. Ngan, B.-Y.; Chen-Levy, Z.; Weiss, L. M.; Warnke, R. A.; Cleary, M. L. : Expression in non-Hodgkin's lymphoma of the BCL-2 protein associated with the t(14;18) chromosomal translocation. New Eng. J. Med. 318: 1638-1644, 1988. 2. Hockenbery, D.; Nunez, G.; Milliman, C.; Schreiber, R. D.; Korsmeyer, S. J. : Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348: 334-336, 1990.
• Gene Name
  BCL2
• Protein Name
  Apoptosis regulator Bcl-2
• Gene Full Name
  B-cell CLL/lymphoma 2
• Synonyms
  PPP1R50|protein phosphatase 1, regulatory subunit 50|ONCOGENE B-CELL LEUKEMIA 2
• Uniprot ID
  Human(P10415), Mouse(P10417), Rat(P49950)
• Entrez GeneID
  Human(596), Mouse(12043), Rat(24224)
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Bcl2   Bcl-2-100  
• Gene symbol
  SCARNA3, MIR100, TMED5, PVT1, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2
• Short name
  Bcl2 Antibody ( Bcl-2-100)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  B-cellular CLL/lymphoma 2 (antibody to-) ( Bcl-2-100)
• Alternative technique
  antibodies
• Alternative to gene target
  B-cell CLL/lymphoma 2, Bcl-2 and PPP1R50, BCL2 and IDBG-4354 and ENSG00000171791 and 596, protein phosphatase 2A binding, nuclei, Bcl2 and IDBG-185673 and ENSMUSG00000057329 and 12043, BCL2 and IDBG-645006 and ENSBTAG00000019302 and 281020

Gene info

• Identity
  HGNC:32577
• Gene
  SCARNA3
• Long gene name
  small Cajal body-specific RNA 3
• Synonyms
  • HBI-100
• Locus
  1q25.1
• Discovery year
  2006-03-31
• Entrez gene record
  677679
• Pubmed identfication
  • 11387227
• RefSeq identity
  • NR_002998
• Classification
  • Small Cajal body-specific RNAs

Gene info

• Identity
  HGNC:31487
• Gene
  MIR100
• Long gene name
  microRNA 100
• Synonyms gene
  • MIRN100
• Synonyms
  • hsa-mir-100
• Locus
  11q24.1
• Discovery year
  2004-04-23
• Entrez gene record
  406892
• RefSeq identity
  • NR_029515
• Classification
  • MicroRNA MIR10/100 family

Gene info

• Identity
  HGNC:24251
• Gene
  TMED5
• Long gene name
  transmembrane p24 trafficking protein 5
• Synonyms gene name
  • transmembrane emp24 protein transport domain containing 5
• Synonyms
  • CGI-100
  • p24g2
  • p24gamma2
• GenBank acession
  • BC070051
• Locus
  1p22.1
• Discovery year
  2004-12-21
• Entrez gene record
  50999
• Pubmed identfication
  • 10810093
• RefSeq identity
  • NM_016040
• Classification
  • Transmembrane p24 trafficking proteins
• VEGA ID
  OTTHUMG00000010162

Gene info

• Identity
  HGNC:9709
• Gene
  PVT1
• Long gene name
  Pvt1 oncogene
• Synonyms gene name
  • pvt-1 (murine) oncogene homolog, MYC activator
  • Pvt1 oncogene homolog (mouse)
  • Pvt1 oncogene (non-protein coding)
• Synonyms
  • NCRNA00079
  • LINC00079
  • onco-lncRNA-100
  • MIR1204HG
• Synonyms name
  • non-protein coding RNA 79
  • long intergenic non-protein coding RNA 79
  • MIR1204, MIR1205, MIR1206 and MIR1207 host gene
  • plasmacytoma variant translocation 1
• GenBank acession
  • M31519
• Locus
  8q24.21
• Discovery year
  2001-06-22
• Entrez gene record
  5820
• Pubmed identfication
  • 17503467
  • 23801869
• RefSeq identity
  • NR_003367
• Classification
  • Long non-coding RNAs with non-systematic symbols
  • MicroRNA non-coding host genes
• VEGA ID
  OTTHUMG00000164871

Gene info

• Identity
  HGNC:31639
• Gene
  MIR7-2
• Long gene name
  microRNA 7-2
• Synonyms gene
  • MIRN7-2
• Synonyms
  • hsa-mir-7-2
• Locus
  15q26.1
• Discovery year
  2004-04-23
• Entrez gene record
  407044
• RefSeq identity
  • NR_029606
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:32051
• Gene
  MIR329-2
• Long gene name
  microRNA 329-2
• Synonyms gene
  • MIRN329-2
• Synonyms
  • hsa-mir-329-2
• Locus
  14q32.31
• Discovery year
  2005-07-11
• Entrez gene record
  574409
• RefSeq identity
  • NR_029968
• Classification
  • MicroRNA MIR329 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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