Nck1 Antibody
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Catalog numberbs-50475R
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PricePlease ask
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Size0.1ml
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Long nameNck1 Primary Polyclonal Antibody
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Also known asNck1 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenNck1
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SpecificityThis is a highly specific antibody against Nck1.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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SourceSynthetic Peptide
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Gene ID number4690
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Swiss ProtP16333
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Tested ApplicationsWB
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Recommended dilutionsWB (1:2,000)
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Cross reactivityHuman, Mouse
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenAdapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesNCK; nck-1; NCKalpha; Cytoplasmic protein NCK1; NCK adaptor protein 1; SH2/SH3 adaptor protein NCK-alpha; NCK1
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolNCK1-DT, NCK1
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Short nameAnti-Nck1
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameNck1 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetNCK adaptor protein 1, NCK and nck-1 and NCKalpha, NCK1 and IDBG-58017 and ENSG00000158092 and 4690, receptor tyrosine kinase binding, nuclei, Nck1 and IDBG-193200 and ENSMUSG00000032475 and 17973, NCK1 and IDBG-638662 and ENSBTAG00000018427 and 536154
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Gene info
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Identity
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Gene
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Long gene nameNCK1 divergent transcript
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Synonyms gene
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Synonyms gene name
- NCK1 antisense RNA 1 (head to head)
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Synonyms
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Synonyms name
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Locus
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Discovery year2014-01-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Divergent transcripts
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNCK adaptor protein 1
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-11-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SH2 domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data