CCL4 Antibody / MIP-1 beta

• Catalog number
  R31955
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CCL4 / MIP-1 beta
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,ELISA : 0.1-0.5ug/ml
• Notes
  Optimal dilution of the CCL4 antibody should be determined by the researcher.
• Intented use
  This CCL4 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P13236
• Purity
  Antigen affinity
• Description
  Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. And it is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines(11, 14).
• Immunogen
  Amino acids 24-92 of human CCL4 were used as the immunogen for the CCL4 antibody.
• Storage
  After reconstitution, the CCL4 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCL4   MIP-1   beta  
• Gene symbol
  TNPO1, CCL4, CCL3, CCL26, MAPKAP1, MIPEP, CCL23, RPTOR, CCL15, CCL20
• Short name
  Anti-CCL4 / MIP-1 beta
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to CCL4 / MIP-1 beta
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6401
• Gene
  TNPO1
• Long gene name
  transportin 1
• Synonyms gene
  • KPNB2
• Synonyms gene name
  • karyopherin (importin) beta 2
• Synonyms
  • MIP
  • TRN
  • IPO2
  • MIP1
• Synonyms name
  • importin 2
• GenBank acession
  • U70322
• Locus
  5q13.2
• Discovery year
  1997-04-21
• Entrez gene record
  3842
• Pubmed identfication
  • 8808633
  • 9144189
• RefSeq identity
  • NM_002270
• Classification
  • Importins
  • Armadillo like helical domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000100967

Gene info

• Identity
  HGNC:10630
• Gene
  CCL4
• Long gene name
  C-C motif chemokine ligand 4
• Synonyms gene
  • LAG1
  • SCYA4
• Synonyms gene name
  • small inducible cytokine A4 (homologous to mouse Mip-1b)
  • chemokine (C-C motif) ligand 4
• Synonyms
  • MIP-1-beta
  • Act-2
  • AT744.1
• GenBank acession
  • M23502
• Locus
  17q12
• Discovery year
  1990-07-05
• Entrez gene record
  6351
• Pubmed identfication
  • 1972563
• RefSeq identity
  • NM_002984
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188414

Gene info

• Identity
  HGNC:10627
• Gene
  CCL3
• Long gene name
  C-C motif chemokine ligand 3
• Synonyms gene
  • SCYA3
• Synonyms gene name
  • small inducible cytokine A3 (homologous to mouse Mip-1a)
  • chemokine (C-C motif) ligand 3
• Synonyms
  • G0S19-1
  • LD78ALPHA
  • MIP-1-alpha
• GenBank acession
  • M23178
• Locus
  17q12
• Discovery year
  1990-07-05
• Entrez gene record
  6348
• RefSeq identity
  • NM_002983
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188413

Gene info

• Identity
  HGNC:10625
• Gene
  CCL26
• Long gene name
  C-C motif chemokine ligand 26
• Synonyms gene
  • SCYA26
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 26
  • chemokine (C-C motif) ligand 26
• Synonyms
  • MIP-4alpha
  • eotaxin-3
  • IMAC
  • MIP-4a
  • TSC-1
• Synonyms name
  • macrophage inflammatory protein 4-alpha
  • small inducible cytokine A26
  • CC chemokine IMAC
  • chemokine N1
  • thymic stroma chemokine-1
  • eotaxin-3
• GenBank acession
  • AF124601
• Locus
  7q11.23
• Discovery year
  1999-06-09
• Entrez gene record
  10344
• Pubmed identfication
  • 10373330
• RefSeq identity
  • NM_006072
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000130403

Gene info

• Identity
  HGNC:18752
• Gene
  MAPKAP1
• Long gene name
  MAPK associated protein 1
• Synonyms gene name
  • mitogen-activated protein kinase associated protein 1
• Synonyms
  • MGC2745
  • SIN1
  • MIP1
• Synonyms name
  • stress-activated protein kinase-interacting 1
• GenBank acession
  • M37191
• Locus
  9q33.3
• Discovery year
  2002-07-19
• Entrez gene record
  79109
• Pubmed identfication
  • 15363842
• Classification
  • MTOR complex 2
• VEGA ID
  OTTHUMG00000020683

Gene info

• Identity
  HGNC:7104
• Gene
  MIPEP
• Long gene name
  mitochondrial intermediate peptidase
• Synonyms
  • MIP
• Locus
  13q12.12
• Discovery year
  1996-10-30
• Entrez gene record
  4285
• Pubmed identfication
  • 9073519
  • 33669127
• Classification
  • M3 metallopeptidase family
• VEGA ID
  OTTHUMG00000016573

Gene info

• Identity
  HGNC:10622
• Gene
  CCL23
• Long gene name
  C-C motif chemokine ligand 23
• Synonyms gene
  • SCYA23
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 23
  • chemokine (C-C motif) ligand 23
• Synonyms
  • Ckb-8
  • MPIF-1
  • MIP-3
  • CKb8
• GenBank acession
  • U58913
• Locus
  17q12
• Discovery year
  1997-11-14
• Entrez gene record
  6368
• Pubmed identfication
  • 9104803
  • 10409433
• RefSeq identity
  • NM_005064
  • NM_145898
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188409

Gene info

• Identity
  HGNC:30287
• Gene
  RPTOR
• Long gene name
  regulatory associated protein of MTOR complex 1
• Synonyms gene name
  • regulatory associated protein of MTOR, complex 1
• Synonyms
  • KOG1
  • Mip1
  • KIAA1303
  • raptor
• Synonyms name
  • regulatory associated protein of mTOR
• Locus
  17q25.3
• Discovery year
  2009-05-29
• Entrez gene record
  57521
• Pubmed identfication
  • 10718198
  • 12150926
• RefSeq identity
  • NM_020761
• Classification
  • WD repeat domain containing
  • MTOR complex 1
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000177622

Gene info

• Identity
  HGNC:10613
• Gene
  CCL15
• Long gene name
  C-C motif chemokine ligand 15
• Synonyms gene
  • SCYA15
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 15
  • chemokine (C-C motif) ligand 15
• Synonyms
  • HCC-2
  • NCC-3
  • SCYL3
  • MIP-5
  • Lkn-1
  • MIP-1d
  • HMRP-2B
• Synonyms name
  • leukotactin 1
  • CC chemokine 3
  • macrophage inflammatory protein 5
  • chemokine CC-2
  • MIP-1 delta
• GenBank acession
  • AF031587
• Locus
  17q12
• Discovery year
  1997-02-11
• Entrez gene record
  6359
• Pubmed identfication
  • 8661057
• RefSeq identity
  • NM_004167
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188406

Gene info

• Identity
  HGNC:10619
• Gene
  CCL20
• Long gene name
  C-C motif chemokine ligand 20
• Synonyms gene
  • SCYA20
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 20
  • chemokine (C-C motif) ligand 20
• Synonyms
  • LARC
  • MIP-3a
  • exodus-1
  • ST38
  • CKb4
• GenBank acession
  • D86955
• Locus
  2q36.3
• Discovery year
  1997-02-10
• Entrez gene record
  6364
• Pubmed identfication
  • 9038201
  • 11352563
• RefSeq identity
  • NM_004591
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000133189

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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