β -Amyloid Polyclonal Antibody

• Catalog number
  3356-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  β -Amyloid
• Target Alternative Name
  A4 antibody,A4 antibody,A4 human antibody,AAA antibody,AAA antibody,ABETA antibody,ABETA antibody,ABPP antibody,ABPP antibody,AD1 antibody,AICD-50 antibody,AICD-57 antibody,AICD-59 antibody,AID(50) antibody,AID(57) antibody,AID(59) antibody,Alzheimer disease amyloid protein antibody,Alzheimers Disease Amyloid Protein antibody,Amyloid B antibody,Amyloid Beta A4 Protein Precursor antibody,Amyloid Beta antibody,Amyloid intracellular domain 50 antibody,Amyloid intracellular domain 57 antibody,Amyloid intracellular domain 59 antibody,Amyloid of Aging and Alzheimer Disease antibody,APP antibody,APPI antibody,APPI antibody,B Amyloid antibody,Beta APP antibody,Beta-APP40 antibody,Beta-APP42 antibody,C31 antibody,Cerebral Vascular Amyloid Peptide antibody,CTFgamma antibody,CVAP antibody,CVAP antibody,Gamma-CTF(50) antibody,Gamma-CTF(57) antibody,Gamma-CTF(59) antibody,PN II antibody,PN-II antibody,PN2 antibody,PreA4 antibody,PreA4 antibody,Protease nexin II antibody,Protease nexin-II antibody,S-APP-alpha antibody,S-APP-beta antibody.
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthetic peptide mapping to the N-terminus of human beta-amyloid
• Accession
  P05067
• Gene Id
  351
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit anti-β -Amyloid polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
• Purification
  Affinity purified rabbit IgG
• Application
  Western blot
• Positive Control
  Western Blot
• Application And Usages
  Western blot: 1-4 µg
• Description
  Amyloid deposition is associated with a variety of neurological disorders, including Alzheimer’s disease, type II diabetes and Down’s syndrome. The amyloid precursor protein (APP) undergoes alternative splicing, resulting in several isoforms. Proteolytic cleavage of APP leads to the formation of the 4 kDa amyloid β /A4 protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer patients.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  Amyloid  
• Gene symbol
  APLP1, APLP2
• Short name
  β -Amyloid Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Rabbit IgG
• Alternative name
  β -Amyloid polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:597
• Gene
  APLP1
• Long gene name
  amyloid beta precursor like protein 1
• Synonyms gene name
  • amyloid beta (A4) precursor-like protein 1
• Synonyms
  • APLP
• Synonyms name
  • amyloid-like protein 1
  • amyloid precursor-like protein 1
• GenBank acession
  • U48437
• Locus
  19q13.12
• Discovery year
  1992-06-18
• Entrez gene record
  333
• Pubmed identfication
  • 8432545
• RefSeq identity
  • NM_001024807
• VEGA ID
  OTTHUMG00000180692

Gene info

• Identity
  HGNC:598
• Gene
  APLP2
• Long gene name
  amyloid beta precursor like protein 2
• Synonyms gene
  • APPL2
• Synonyms gene name
  • amyloid beta (A4) precursor-like protein 2
• Synonyms
  • APPH
• GenBank acession
  • L19597
• Locus
  11q24.3
• Discovery year
  1993-06-23
• Entrez gene record
  334
• Pubmed identfication
  • 10702673
• RefSeq identity
  • NM_001642
• VEGA ID
  OTTHUMG00000165767

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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