NHERF1 / EBP50 monoclonal antibody
-
Catalog number11-348-C100
-
PricePlease ask
-
Size100ug
-
-
Long nameMouse Monoclonal Antibody against Human NHERF1 / EBP50, Clone: EBP-10
-
AntigenNHERF1 / EBP50
-
Species reactivityOther not tested, Human (Homo sapiens)
-
Negative species reactivityat the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
-
ClonalityMonoclonal Antibody (Mab)
-
CloneEBP-10
-
ApplicationsIP, WB, IHC(P)
-
ImmunogenBacterially produced recombinant full-length human NHERF1.
-
Format conjugationpurified; unconjugated
-
SpecificityThe antibody EBP-10 reacts with NHERF1/EBP50 phosphoprotein of 50 kDa, which serves as an adaptor and regulator protein.
-
Research areaCytoskeleton: Actin System, Cytoskeleton: Actin System (Human), Adaptor Proteins (Human), Adaptor Proteins
-
Concentration1 mg/ml
-
Storage bufferPhosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
-
Shipping and storageMouse Monoclonal Antibody against Human NHERF1 / EBP50, Clone: EBP-10 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
-
BackgroundNHERF1 (Na+/H+ exchanger regulatory factor 1), also known as EBP50 (ezrin, radixin, moesin-binding phosphoprotein 50) is an adaptor protein, which associates with beta-catenin and is required for its localization at the cell-cell junctions, interacts with various G protein-coupled receptors and regulates their traffic, as well as sodium-hydrogen exchange and sodium-dependent phosphate transport. NHERF1/EBP50 inhibits cell motility and is required to suppress anchorage-independent growth. It contains C-terminal ERM (ezrin, radixin, moesin)-binding region and two N-terminal PDZ (postsynaptic-density-95/disc-large/ZO1 homology) domains and is able to form head-to-tail intramolecular conformation to regulate its interactions.
-
Purity> 95% (by SDS-PAGE)
-
Purification methodPurified by protein-A affinity chromatography
-
ReferencesContact us for the most recent list of references
-
PropertiesIf you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
French translationanticorps
-
Gene target
-
Gene symbolSLC9A3R1
-
Short nameAnti-NHERF1 / EBP50 Mab
-
TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
-
HostMouse (Mus musculus)
-
IsotypeIgG2b
-
Alternative nameMouse Monoclonal to NHERF1 / EBP50
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameSLC9A3 regulator 1
-
Synonyms gene name
- solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1
- solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1
- solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
- solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-02-26
-
Entrez gene record
-
Pubmed identfication
-
Classification
- PDZ domain containing
- MicroRNA protein coding host genes
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data