NHERF1 / EBP50 monoclonal antibody

  • Catalog number
    11-348-C100
  • Price
    Please ask
  • Size
    100ug
  • Long name
    Mouse Monoclonal Antibody against Human NHERF1 / EBP50, Clone: EBP-10
  • Antigen
    NHERF1 / EBP50
  • Species reactivity
    Other not tested, Human (Homo sapiens)
  • Negative species reactivity
    at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
  • Clonality
    Monoclonal Antibody (Mab)
  • Clone
    EBP-10
  • Applications
    IP, WB, IHC(P)
  • Immunogen
    Bacterially produced recombinant full-length human NHERF1.
  • Format conjugation
    purified; unconjugated
  • Specificity
    The antibody EBP-10 reacts with NHERF1/EBP50 phosphoprotein of 50 kDa, which serves as an adaptor and regulator protein.
  • Research area
    Cytoskeleton: Actin System, Cytoskeleton: Actin System (Human), Adaptor Proteins (Human), Adaptor Proteins
  • Concentration
    1 mg/ml
  • Storage buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
  • Shipping and storage
    Mouse Monoclonal Antibody against Human NHERF1 / EBP50, Clone: EBP-10 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
  • Background
    NHERF1 (Na+/H+ exchanger regulatory factor 1), also known as EBP50 (ezrin, radixin, moesin-binding phosphoprotein 50) is an adaptor protein, which associates with beta-catenin and is required for its localization at the cell-cell junctions, interacts with various G protein-coupled receptors and regulates their traffic, as well as sodium-hydrogen exchange and sodium-dependent phosphate transport. NHERF1/EBP50 inhibits cell motility and is required to suppress anchorage-independent growth. It contains C-terminal ERM (ezrin, radixin, moesin)-binding region and two N-terminal PDZ (postsynaptic-density-95/disc-large/ZO1 homology) domains and is able to form head-to-tail intramolecular conformation to regulate its interactions.
  • Purity
    > 95% (by SDS-PAGE)
  • Purification method
    Purified by protein-A affinity chromatography
  • References
    Contact us for the most recent list of references
  • Properties
    If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    SLC9A3R1
  • Short name
    Anti-NHERF1 / EBP50 Mab
  • Technique
    Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
  • Host
    Mouse (Mus musculus)
  • Isotype
    IgG2b
  • Alternative name
    Mouse Monoclonal to NHERF1 / EBP50
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    SLC9A3 regulator 1
  • Synonyms gene name
    • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1
    • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1
    • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
    • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1999-02-26
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • PDZ domain containing
    • MicroRNA protein coding host genes
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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