EDG1 (Endothelial Cell Differentiation Gene 1) (APC)

Products_type

Antibody
Products_short_name

[EDG1]
Products_name_syn

[Anti -EDG1 (Endothelial Cell Differentiation Gene 1) (APC)]
Other_names

[EDG1; EDG1; sphingosine 1-phosphate receptor 1; S1P receptor 1; OTTHUMP00000012525; S1P receptor Edg-1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; sphingosine-1-phosphate receptor 1]
Other_gene_names

[S1PR1; EDG1; EDG1; S1P1; ECGF1; EDG-1; CHEDG1; D1S3362; FLJ58121]
Clonality

Monoclonal
Clone

[8H120]
Reactivity

Human
Specificity

Recognizes human EDG1.
Purity

Purified by Protein G affinity chromatography from hybridoma tissue culture supernatant.
Form

Supplied as a liquid in saline,
Concentration

0.01mg/ml
Storage_stability

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. F
Tested_application

Flow Cytometry (FC/FACS)
Description

For cells, cell lines and tissues in culture till half confluency. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.

Gene target

EDG1 Endothelial Differentiation Gene APC
Gene symbol

APC, S1PR1, HEXIM1
Short name

EDG1 (Endothelial Differentiation 1) (APC)
Host

Mouse
Isotype

IgG2b
Label

APC
Alternative name

EDG1 (Endothelial cellular Differentiation Gene 1) (adenomatous polyposis coli)
Alternative to gene target

adenomatous polyposis coli, BTPS2 and DP2 and DP2.5 and DP3 and GS and PPP1R46, APC and IDBG-37007 and ENSG00000134982 and 324, microtubule plus-end binding, nuclei, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT.25770 and IDBG-644937 and ENSBTAG00000018852 and 533233
Tissue

cell

Identity

HGNC:583
Gene

APC
Long gene name

APC regulator of WNT signaling pathway
Synonyms gene name
- adenomatosis polyposis coli
- adenomatous polyposis coli
- APC, WNT signaling pathway regulator
Synonyms
- DP2
- DP3
- DP2.5
- PPP1R46
Synonyms name
- protein phosphatase 1, regulatory subunit 46
GenBank acession
- M74088
Locus

5q22.2
Discovery year

1986-01-01
Entrez gene record

324
Pubmed identfication
- 1651563
RefSeq identity
- NM_000038
Classification
- Protein phosphatase 1 regulatory subunits
- Armadillo repeat containing
VEGA ID

OTTHUMG00000128806
Locus Specific Databases

Identity

HGNC:3165
Gene

S1PR1
Long gene name

sphingosine-1-phosphate receptor 1
Synonyms gene
- EDG1
Synonyms gene name
- endothelial differentiation, sphingolipid G-protein-coupled receptor, 1
Synonyms
- edg-1
- D1S3362
- CD363
GenBank acession
- M31210
Locus

1p21.2
Discovery year

1998-05-15
Entrez gene record

1901
Pubmed identfication
- 2160972
- 9488656
RefSeq identity
- NM_001400
Classification
- CD molecules
- Sphingosine 1-phosphate receptors
VEGA ID

OTTHUMG00000010835