Anti-Fibrinogen Antibody

• Catalog number
  A1708-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Fibrinogen
• Target Alternative Name
  Fibrinogen alpha chain, Fibrinopeptide A, Fibrinopeptide A, FGA
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Human fibrinogen (Cat# 7692)
• Accession
  P02671
• Gene Id
  2243
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  In PBS, 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
• Purification
  Affinity purified
• Application
  Dot Blot,Western Blotting
• Description
  Fibrinogen is an acute phase protein that is part of the coagulation cascade of proteins. The end result of the cascade is the production of thrombin that converts fibrinogen to fibrin. Thrombin rapidly proteolysis fibrinogen, releasing fibrinopeptide A. The loss of this small peptide is not sufficient to make the resulting fibrin molecule insoluble, but it tends to form complexes with adjacent fibrin and fibrinogen molecules. Thrombin then cleaves a second peptide, fibrinopeptide B, from fibrin and the fibrin monomers formed then polymerize spontaneously to form an insoluble gel. The polymerized fibrin is held together by noncovalent and electrostatic forces and stabilized by the transamidating enzyme, factor XIIIa that is produced by the action of thrombin on factor XIII. The insoluble fibrin aggregates (clots) and aggregated platelets then block the damaged blood vessel and prevent further bleeding. The amount of fibrinogen in the plasma can serve as a nonspecific indicator of whether or not an inflammatory process is present in the body. Fibrinogen from any mammalian source will be cleaved by thrombin from any mammalian source.
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Not Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Fibrinogen  
• Gene symbol
  FGG, FGB, FGA
• Short name
  Anti-Fibrinogen Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  IgG
• Alternative name
  Antibody toFibrinogen (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3694
• Gene
  FGG
• Long gene name
  fibrinogen gamma chain
• Synonyms gene name
  • fibrinogen, gamma polypeptide
• Locus
  4q32.1
• Discovery year
  2001-06-22
• Entrez gene record
  2266
• RefSeq identity
  • NM_021870
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000150329
• Locus Specific Databases
  • LOVD EAHAD Coagulation Factor Variant Database
  • LRG_585

Gene info

• Identity
  HGNC:3662
• Gene
  FGB
• Long gene name
  fibrinogen beta chain
• Synonyms gene name
  • fibrinogen, B beta polypeptide
• Locus
  4q31.3
• Discovery year
  2001-06-22
• Entrez gene record
  2244
• RefSeq identity
  • NM_005141
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000150331
• Locus Specific Databases
  • LRG_558

Gene info

• Identity
  HGNC:3661
• Gene
  FGA
• Long gene name
  fibrinogen alpha chain
• Synonyms gene name
  • fibrinogen, A alpha polypeptide
• Locus
  4q31.3
• Discovery year
  2001-06-22
• Entrez gene record
  2243
• RefSeq identity
  • NM_000508
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000150330
• Locus Specific Databases
  • LRG_557

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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