BRD3-BD1 Antibody

• Catalog number
  6665-100
• Price
  Please ask
• Size
  100 μg

• Antibody Target
  BRD3-BD1
• Target Alternative Name
  KIAA0043, RING3L
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human BRD3-BD1 (Cat # 7256)
• Accession
  Q15059
• Gene Id
  8019
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
• Purification
  Affinity Purified Antibody
• Application
  Western blot
• Positive Control
  Western Blot: Recombinant protein
• Application And Usages
  Western blot: 1-4 µg/ml.
• Description
  The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. BRD3 binds hyper-acetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. It regulates transcription by promoting the binding of the transcription factor GATA1 to its targets and transcription of the CCND1 gene. A chromosomal aberration involving BRD3 was found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BRD3-BD1  
• Gene symbol
  BRD3, DEFB1
• Short name
  BRD3-BD1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  BRD3-BD1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1104
• Gene
  BRD3
• Long gene name
  bromodomain containing 3
• Synonyms gene name
  • bromodomain-containing 3
• Synonyms
  • RING3L
  • ORFX
  • KIAA0043
• Synonyms name
  • RING3-like
• Locus
  9q34.2
• Discovery year
  2000-07-25
• Entrez gene record
  8019
• Pubmed identfication
  • 7584044
  • 8781126
• RefSeq identity
  • NM_007371
• Classification
  • Bromodomain containing
  • Bromodomain and extra-terminal domain family
• VEGA ID
  OTTHUMG00000021004

Gene info

• Identity
  HGNC:2766
• Gene
  DEFB1
• Long gene name
  defensin beta 1
• Synonyms gene name
  • defensin, beta 1
• Synonyms
  • HBD-1
  • DEFB-1
  • DEFB101
  • HBD1
  • BD1
  • MGC51822
• Synonyms name
  • beta-defensin 1
  • beta defensin 1
• GenBank acession
  • X92744
• Locus
  8p23.1
• Discovery year
  1997-05-29
• Entrez gene record
  1672
• Pubmed identfication
  • 7628632
• RefSeq identity
  • NM_005218
• Classification
  • Defensins, beta
• VEGA ID
  OTTHUMG00000090367

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products