Target of this antibody:
Alternative names of antibody target:
Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, AAT, PI
Alpha 1 Antitrypsin is an acute-phase plasma protein found at 290 mg per 100 ml. It functions as a serine protease inhibitor with targets like elastase, plasmin, collagenase, thrombin, leucocyte proteases, trypsin, chymotrypsin, and plasminogen activator. Clinically, its deficiency is associated with two major diseases: pulmonary emphysema and early onset/juvenile hepatic cirrhosis. It is elevated in inflammatory conditions, malignancies, liver disease and pregnancy and also after surgical trauma and use of oral contraceptives. The simultaneous quantitative determination of alpha-1-PI and ceruloplasmin permits differential diagnosis of liver afflictions. Rise in alpha 1 antitrypsin occurs as an acute phase response to tissue necrosis and inflammation.
Clonality of antibody:
This antibody reacts with:
Human, Mouse, Rat
Human alpha1 antitrypsin (Cat # 7294)
Concentration of antibody:
Form of antibody:
Affinity purified rabbit IgG
This antibody has been succesfully tested for use in following methods:
Western blot: 1-4 µg
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
anti-Alpha1 Antitrypsin Antibody
antibody to-Alpha1 Antitrypsin (Antibody to)