IL-24 Recombinant Protein

• Catalog number
  40-600
• Price
  Please ask
• Size
  0.005 mg, 0.02 mg

• About recombinant protein
  IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.
• Other name of the recombinant
  C49A, FISP, MDA7, MOB5, ST16, IL10B, Interleukin-24, Melanoma differentiation-associated gene 7 protein, IL-24
• Recombinant in
  CHO cells
• SEQUENCE
  QEFHFGPCQV KGVVPQKLWE AFWAVKDTMQ AQDNITSARL LQQEVLQNVS DAESCYLVHT LLEFYLKTVF KNYHNRTVEV RTLKSFSTLA NNFVLIVSQL QPSQENEMFS IRDSAHRRFL LFRRAFKQLD VEAALTKALG EVDILLTWMQ KFYKLHHHHH H
• Keep at
  The lyophilized IL-24 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-24 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-24 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  297632401
• Accession nr
  NP_001172085.1
• Pureity
  Greater than 95% by SDS-PAGE gel and HPLC analyses.
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  11009
• Gene name
  interleukin 24
• Source
  Homo sapiens
• Uniprot
  Q13007
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL-24   Protein  
• Gene symbol
  IL24
• Short name
  IL-24 Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Interleukin-24 Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:11346
• Gene
  IL24
• Long gene name
  interleukin 24
• Synonyms gene
  • ST16
• Synonyms
  • mda-7
  • IL10B
  • Mob-5
  • C49A
  • FISP
  • IL-24
• Synonyms name
  • melanoma differentiation association protein 7
  • suppression of tumorigenicity 16 (melanoma differentiation)
  • IL-4-induced secreted protein
• GenBank acession
  • U16261
• Locus
  1q32.1
• Discovery year
  1999-12-02
• Entrez gene record
  11009
• Pubmed identfication
  • 8545104
  • 8799171
• RefSeq identity
  • NM_006850
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000036459

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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