HDAC3 Antibody

• Catalog number
  3603-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  HDAC3
• Target Alternative Name
  SMAP45 , HD3 , RPD3 , RPD3-2
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat, chicken
• Immunogen Sequence
  Synthetic peptide corresponding to the C-terminus of human HDAC-3
• Accession
  NP_003874
• Gene Id
  8841
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.2 mg/ml
• Formulation
  30 µg (0.2 mg/ml) peptide affinity purified rabbit anti-HDAC3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Immunohistochemistry
• Application And Usages
  Western blotting (0.5-4 µg/ml)and Immunohistochemistry (20-30 µg/ml). However, the optimal conditions should be determined individually.The antibody detects the 49 kDa HDAC3. It does not cross-react with other HDAC proteins including HDAC1, 2, 4, 5, 6, 7, and 8. Jurkat cell lysate (Cat.# 2401-100) can be used as a positive control.
• Description
  HDAC3 is a member of the class I mammalian histone deacetylase family, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC3 is composed of 428 amino acid residues. HDAC3 interacts with a growing number of transcriptional factors including SMRT and N-CoR. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HDAC3  
• Gene symbol
  HDAC3
• Short name
  HDAC3 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  histone deacetylase 3 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  histone deacetylase 3, HD3 and RPD3 and RPD3-2, HDAC3 and IDBG-50725 and ENSG00000171720 and 8841, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac3 and IDBG-140814 and ENSMUSG00000024454 and 15183, HDAC3 and IDBG-646121 and ENSBTAG00000017360 and 404125

Gene info

• Identity
  HGNC:4854
• Gene
  HDAC3
• Long gene name
  histone deacetylase 3
• Synonyms
  • RPD3
  • HD3
  • RPD3-2
  • KDAC3
• GenBank acession
  • AF059650
• Locus
  5q31.3
• Discovery year
  1999-01-29
• Entrez gene record
  8841
• Pubmed identfication
  • 9501169
  • 9464271
• RefSeq identity
  • NM_003883
• Classification
  • NCoR/SMRT transcriptional repression complex subunits
  • Histone deacetylases, class I
• VEGA ID
  OTTHUMG00000129629

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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