Montelukast sodium, Leukotriene CysLT1 antagonist
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Catalog number
SIH-538-50MG
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Price
Please ask
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Size
50 mg
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Stock availabilitIn Stock
In Stock
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CAS number
151767-02-1
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Description
Leukotriene CysLT1 antagonist
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Molecular weight
608,2 g/mol
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Primary research fields
Immunology, Innate Immunity, Macrophage
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Other name
1-[[[(1R)-1-[3-(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]-methyl]-cyclopropaneacetic acid, monosodium salt, Montelukast sodium, Montelukast monosodium salt, MK-0476, MK-476, KS-1087
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Product category
Small Molecules
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Product type
Antagonist
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Chemical formula
C35H35ClNO3S • Na
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Origin
Synthetic
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Purity pourcentage
>98% (HPLC); NMR (Conforms)
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Soluble in
Soluble in DMSO (50 mg/ml), or water (30 mg/ml), or ethanol (60 mg/ml)
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Physical appearance
Powder
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Storage recommendations
-20ºC
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Shipping recommendations
Shipped Ambient
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Safety information
Classification: D2A Very Toxic Material Causing Other Toxic Effects - Reproductive hazard E Corrosive Material - Corrosive to skin Hazard statement(s): H318 Causes serious eye damage. H361fd Suspected of damaging fertility. Suspected of damaging the unborn child. Precautionary statement(s): P280 Wear protective gloves/ eye protection/ face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
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PubChem number
23663996
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Scientific context
Montelukast is a cysteinyl leukotriene receptor 1 (CysLT1) antagonist. It blocks pentylenetetrazole-induced seizures, blood brain barrier disruption and leukocyte migration in mice.
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Release date
30/Aug/2016
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PubMed number
Refer to PubMed
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Tested applications
To be tested
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Tested reactivity
To be tested
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Representative figure legend
Chemical structure of Montelukast sodium (SIH-538), a Leukotriene CysLT1 antagonist. CAS #: 151767-02-1. Molecular Formula: C35H35ClNO3S • Na. Molecular Weight: 608.2 g/mol. Chemical structure of Montelukast sodium, a Leukotriene CysLT1 antagonist (SIH-538). CAS # 151767-02-1. Molecular Formula: C35H35ClNO3S • Na.
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Warning information
Non-hazardous
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Country of production
Canada
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Total weight kg
0.25
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Net weight g
0.05
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Additional description
The antagonist receptor ligand binding will be in contrast with agonist activity. stressma produces more antagonist and receptor related products as 1.
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Gene target
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Short name
Montelukast sodium, Leukotriene CysLT1 antagonist
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Alternative name
Montelukast sodium, Leukotriene CysLT1 antagonist
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