Phospho-ALIX polyconal Antibody

• Catalog number
  A1044-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  PDCD6IP
• Target Alternative Name
  AIP1, ALIX, KIAA1375, HP95, DRIP4
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Accession
  Q8WUM4
• Gene Id
  10015
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  100 ug (1 mg/ml) of antibody in 0.01M Tris-HCl, pH 8.0, 0.15M NaCl, and 0.02% sodium azide.
• Purification
  Affinity purified rabbit IgG using protein G
• Application
  WB, Immunoblot
• Application And Usages
  Western blot, Immunoblot: 0.5-2 μg/ml
• Description
  Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Not Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Phospho-ALIX   polyconal  
• Gene symbol
  PDCD6IP
• Short name
  Phospho-ALIX polyconal Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  phosphorilated-ALIX polyconal (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8766
• Gene
  PDCD6IP
• Long gene name
  programmed cell death 6 interacting protein
• Synonyms gene name
  • programmed cell death 6-interacting protein
• Synonyms
  • Alix
  • AIP1
  • Hp95
• Synonyms name
  • ALG-2 interacting protein X
• GenBank acession
  • BC020066
• Locus
  3p22.3
• Discovery year
  1999-12-10
• Entrez gene record
  10015
• Pubmed identfication
  • 9880530
• VEGA ID
  OTTHUMG00000130751

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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