Human Recombinant FKBPL

• Catalog number
  6345-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  Human Recombinant FKBPL
• Alternative_names
  FK506 binding protein like, DIR1, NG7, WISP39.
• Description
  An immunophilin family protein functioning as a protein folding chaperone
• Recombinant
  Yes
• Source
  E. Coli
• Purity by SDS PAGE
  ≥90%
• Assay
  SDS-PAGE
• Biological activity
  Specific activity is > 210 nmoles/min/mg.
• Unit Definition
  Specific activity is defined as the amount of enzyme that cleaves 1 µmole of suc-AAFP-pNA per minute at 25°C in Tris HCl pH 8.0 using chymotrypsin.
• Molecular Weight
  39.2 kDa
• Storage Temp
  -20°C
• Shipping
  gel pack
• Shelf Life
  12 months
• Concentration
  0.25 mg/ml
• Appearance
  Liquid
• Physical form description
  0.25 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 20% glycerol, 1 mM EDTA and 100 mM NaCl.
• Background Information
  FKBPL is related to the immunophilin protein family, which take part in immunoregulation and regular cellular processes involving protein folding and trafficking. FKBPL has an important function in the induced radio resistance and participates in the control of the cell cycle. FKBPL has a role in cellular response to stress. FKBPL interacts with Hsp90, glucocorticoid receptor and dynamitin and is involved in signaling, like other FKBPs.
• Amino acid sequence
  METPPVNTIG EKDTSQPQQE WEKNLRENLD SVIQIRQQPR DPPTETLELE VSPDPASQIL EHTQGAEKLV AELEGDSHKS HGSTSQMPEA LQASDLWYCP DGSFVKKIVI RGHGLDKPKL GSCCRVLALG FPFGSGPPEG WTELTMGVGP WREETWGELI EKCLESMCQG EEAELQLPGH SGPPVRLTLA SFTQGRDSWE LETSEKEALA REERARGTEL FRAGNPEGAA RCYGRALRLL LTLPPPGPPE RTVLHANLAA CQLLLGQPQL AAQSCDRVLE REPGHLKALY RRGVAQAALG NLEKATADLK KVLAIDPKNR AAQEELGKVV IQGKNQDAGL AQGLRKMFGL EHHHHHH
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  FKBPL  
• Gene symbol
  FKBPL
• Short name
  Recombinant FKBPL
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  H. sapiens Rec. FK506 binding protein like
• Alternative technique
  rec
• Alternative to gene target
  FK506 binding protein like, FKBPL and IDBG-80270 and ENSG00000204315 and 63943, FK506 binding, Cytoplasm, Fkbpl and IDBG-172572 and ENSMUSG00000033739 and 56299, BT.24583 and IDBG-633141 and ENSBTAG00000037781 and 513929

Gene info

• Identity
  HGNC:13949
• Gene
  FKBPL
• Long gene name
  FKBP prolyl isomerase like
• Synonyms gene name
  • FK506-binding protein like
  • FK506 binding protein like
• Synonyms
  • DIR1
  • NG7
  • WISp39
• Synonyms name
  • WAF-1/CIP1 stabilizing protein 39
• GenBank acession
  • AF139374
• Locus
  6p21.32
• Discovery year
  2001-04-06
• Entrez gene record
  63943
• Pubmed identfication
  • 9056895
• Classification
  • Tetratricopeptide repeat domain containing
  • FKBP prolyl isomerases
• VEGA ID
  OTTHUMG00000031129

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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