BDNF Antibody (CT)

• Catalog number
  6725-100
• Price
  Please ask
• Size
  100 μl

• Antibody Target
  BDNF
• Target Alternative Name
  BDNF; Brain-derived neurotrophic factor; Abrineurin
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  This BDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the C-terminal region of human BDNF.
• Accession
  P23560
• Gene Id
  627
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  100 µl of antibody in PBS with 0.09% (W/V) sodium azide
• Purification
  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Application
  Western blot, IHC
• Positive Control
  Western blot: CEM cell line, IHC: human brain tissue, FACS: CEM cells, IF: NCI-H460 cells
• Application And Usages
  Western blot: ~1:1000, IHC: ~1:10–1:50, IF: ~1:10–1:50, FC: ~1:10–1:50.
• Description
  Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. Three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4) (also designated NT-5). These various neurotrophins stimulate the in vitro survival of distinct, but partially overlapping, populations of neurons. The cell surface receptors through which neurotrophins mediate their activity have been identified. For instance, the Trk A receptor is the preferential receptor for NGF, but also binds NT-3 and NT-4. The Trk B receptor binds both BDNF and NT-4 equally well, and binds NT-3 to a lesser extent, while the Trk C receptor only binds NT-3.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BDNF  
• Gene symbol
  BDNF, BDNF-AS
• Short name
  BDNF Antibody (CT)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  brain-derived neurotrophic factor (antibody to-) (CT)
• Alternative technique
  antibodies
• Alternative to gene target
  brain-derived neurotrophic factor, ANON2 and BULN2, BDNF and IDBG-36817 and ENSG00000176697 and 627, growth factor activity, Extracellular, Bdnf and IDBG-195506 and ENSMUSG00000048482 and 12064, BDNF and IDBG-636102 and ENSBTAG00000008134 and 617701

Gene info

• Identity
  HGNC:1033
• Gene
  BDNF
• Long gene name
  brain derived neurotrophic factor
• Synonyms name
  • neurotrophin
• GenBank acession
  • AB038670
• Locus
  11p14.1
• Discovery year
  1991-01-15
• Entrez gene record
  627
• Pubmed identfication
  • 2236018
  • 1889806
  • 17942328
  • 17493809
• RefSeq identity
  • NM_170735
• Classification
  • Neurotrophins
• VEGA ID
  OTTHUMG00000178797

Gene info

• Identity
  HGNC:20608
• Gene
  BDNF-AS
• Long gene name
  BDNF antisense RNA
• Synonyms gene
  • BDNFOS
• Synonyms gene name
  • BDNF opposite strand (non-protein coding)
  • BDNF antisense RNA (non-protein coding)
• Synonyms
  • BT2A
  • BT2B
  • BT2C
  • BT2D
  • NCRNA00049
  • BDNF-AS1
  • BDNFAS
• Synonyms name
  • non-protein coding RNA 49
  • BDNF antisense RNA 1 (non-protein coding)
• GenBank acession
  • AY054391
• Locus
  11p14.1
• Discovery year
  2005-02-01
• Entrez gene record
  497258
• Pubmed identfication
  • 15666411
  • 22446693
  • 28777258
• RefSeq identity
  • NR_002832
• Classification
  • Antisense RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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